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High Blood Pressure

Bendroflumethiazide

Bendroflumethiazide is a medicine that’s used to treat oedema (build-up of fluid) and hypertension (high blood pressure). It’s a thiazide diuretic, which means that it gets rid of excess fluid in the body. Because of this, you may notice that you need to urinate more than usual.


In the case of hypertension, it reduces blood pressure by releasing the fluid in the blood vessels, helping to control your blood pressure and maintain it at a normal level.


Bendroflumethiazide has many interactions with other medicines, so before ordering it through Doctor4U, you should check that you aren’t taking any other drugs which may cause a dangerous interaction. Always disclose all of your current medicines in our patient questionnaire so that we can prove the best care possible.



Bendroflumethiazide Patient Information Leaflet

Last Patient Information Leaflet Review: 22/01/2020



This medicine is no longer available to request via our online service. If you are still having trouble with your symptoms please visit the NHS website for services in your area.


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Dr. Diana Gall GMC No. 7685129

Dr Diana Gall graduated from medical school in 2005 and has since undertaken further intensive training in many different areas of medicine. Dr Diana has reached consultant level and has practiced medicine all over Europe.

Shamir Patel GPHC No. 2049338

Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Bendroflumethiazide

Bendroflumethiazide is a thiazide diuretic (more commonly known as water tablets). Despite being a tablet to treat fluid retention, Bendroflumethiazide also treats hypertension (high blood pressure). It does this by reducing the amount of fluid that’s in the blood vessels, helping to lower and control blood pressure.

Can I take Bendroflumethiazide?

Bendroflumethiazide can cause problems for some people, and it might be dangerous to take with certain conditions. If you’ve been diagnosed with any of the following medical problems, you should talk to your doctor about whether bendroflumethiazide is right for you, or whether you should seek alternative treatments for high blood pressure:

  • Allergy to bendroflumethiazide or any ingredients
  • Severely impaired kidney function
  • Severely impaired liver function
  • High levels of calcium in the blood
  • Low levels of sodium in the blood
  • Low levels of potassium in the blood
  • Gout
  • Addison’s disease
  • Diabetes
  • Systematic lupus erythematosus (SLE)
  • Porphyria

If you think you may have any of the above conditions, you should seek a diagnosis before starting any new medication, not just bendroflumethiazide.

If none of the above conditions apply to you, you can assume that it’s safe for you to take the medication unless you’re taking any of the drugs that it has interactions with?

Does Bendroflumethiazide interact with any other medicines?

Bendroflumethiazide interacts with several medications, and it’s important to check if you’re taking any of them before starting this drug for hypertension. The list of possible interactions includes:

  • ACE inhibitors
  • Alcuronium
  • Allopurinol
  • Aminoglutethamide
  • Amiodarone
  • Amlodipine
  • Amphotericin
  • Baclofen
  • Calcium salts
  • Carbamezapine
  • Carbenoxolone
  • Cisplatin
  • Colestipol
  • Colestyramine
  • Corticosteroids
  • Digoxin
  • Disopyromide
  • Dulfyonylureas
  • Dultiazem
  • Flecainide
  • Gallomine
  • Lidocaine
  • Lithium
  • MAOIs
  • Mexiletine
  • Moxisylyte
  • NSAIDs
  • Oestrogens and COCs
  • Pancuronium
  • Pimozide
  • Prazosin
  • Quinidine
  • Sympathomimetics
  • Theophylline
  • Thiorizadine
  • Tizanidine
  • Toremifine
  • Tricyclic antidepressants
  • Tubocurarine
  • Vitamin D

We’ve alphabetised the list to make it easier for you to find specific medicines. If you take a branded version of a drug, check for the active ingredient and see if it matches any of the drugs on this list. There may be some other treatments similar to those listed above, so we would advise you to disclose all medicines that you take to your doctor or in our patient questionnaire. If you’re unsure, most of the medicines that are on this list include treatments for the following conditions:

  • Asthma
  • Blood sugar levels
  • Cancer
  • Cushing’s syndrome
  • Depression
  • Enlarged prostate
  • Epilepsy
  • Fungal infections
  • Gout
  • Heart failure
  • High blood pressure
  • High cholesterol
  • Irregular heartbeat
  • Pain
  • Raynaud’s syndrome
  • Ulcers

If you think you may be taking a medicine that interacts with bendroflumethiazide, please make an appointment with your doctor, or even call into your local pharmacy to ask advice on medication interactions and whether it’s safe for you to take all of your treatments together.

What are the side effects of bendroflumethiazide?

Bendroflumethiazide can cause some unpleasant side effects, but it’s important to remember that hypertension is a serious condition, so you and your GP must make the decision as to whether the benefits of treatment outweigh the potential side effects. Some people are absolutely fine whilst taking bendroflumethiazide, and don’t experience side effects at all. Others might notice mild symptoms, whilst some people suffer. There’s no way of telling how a medicine might affect you until you start taking it. Some of the most commonly reported side effects include:

  • Allergic reaction. If you think you may be allergic to the medicine, stop taking it straight away and seek immediate medical attention. Take the pack of medicine with you to the hospital or urgent care unit.
  • Altered numbers and types of blood cells. Symptoms of this side effect include increased bruising, nosebleeds, sore throat, infections, extreme fatigue, and breathlessness.
  • Decreased tolerance of carbohydrates
  • Worsening of existing diabetes
  • Increased levels of uric acid
  • Worsening of gout
  • Changes in blood lipid levels
  • Low blood potassium levels
  • Low blood magnesium levels
  • High blood calcium levels
  • Nausea
  • Vomiting
  • Diarrhoea
  • Blocked bile flow
  • Increased urination
  • Dizziness

More side effects are in the patient information leaflet that comes with your treatment. It’s important that you read through this thoroughly and understand all of the information inside it. If you have any concerns or don’t understand something, please visit your local pharmacy who will be happy to explain it to you.

If you do experience any side effects of bendroflumethiazide, please report it to your doctor, and then via the MHRA yellow card app. This will help the manufacturers make the patient information leaflet clearer for others.

What happens if I take too much bendroflumethiazide?

An overdose of this medication could be fatal or cause serious problems. If you take more than you need to, you should call 999 and seek emergency treatment. Take the rest of the medicine with you and try to remember how much you’ve already taken.

Can I drive while taking bendroflumethiazide?

Bendroflumethiazide might cause dizziness in some people. So you should always wait to see how the medicine affects you before you decide to drive. If you feel at all unwell, you should avoid driving until you feel better. However, if you’re unaffected by the medication and don’t feel dizzy, drowsy or confused, you should be safe to drive.

How do you take bendroflumethiazide?

Bendroflumethiazide is usually taken once a day. For hypertension, the most common dosage is 2.5mg per day, taken in the morning. If your doctor says that you need to take two tablets per day, you should take the second one around lunchtime.

As bendroflumethiazide is a diuretic, it’s likely to make you urinate more than usual. Because of this, it’s advised that you avoid taking the tablets after 4pm, as you may find yourself getting up frequently during the night and experiencing disturbed sleep.

If you work night shifts, or sleep during the day, you should adjust this advice to fit your own routine and not take the medication for several hours before you go to bed.

Bendroflumethiazide can be taken with or without food, but must be swallowed with a glass of water.

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