UK icon
UK Registered Pharmacy
head shoulders icon
Friendly Patient Support
padlocks icon
Confidential Service
Insomnia (Sleeping Pills)

For delivery by
Order within:
Next Day delivery also available

Circadin PR

Circadin is a medicine that contains melatonin – a hormone that’s naturally produced by the body to regulate our sleep/wake cycles. Circadin is used to treat short-term primary insomnia. The melatonin in Circadin is synthetic, and helps to boost levels of the hormone in those who don’t produce enough of it.

Not getting enough sleep can have a serious impact on your life. It can lower your mood, shorten your temper, increase your likelihood of sleeping in the day, make you drowsy, confused, and make concentrating difficult. If it continues for even more than a few days, it can make both days and nights very difficult, and in the long term it can begin to affect your work and relationships. As Circadin helps you sleep better, it manages these problems so your life is not disrupted.

If you need to take Circadin tablets, you can buy them online safely from a UK doctor such as Doctor-4-U by completing our simple medical questionnaire and getting a certified prescription. It will be dispatched within 24 hours.

This medication can no longer be prescribed for insomnia but it can be prescribed for Jet Lag. Click HERE for more information

1
2
3
4
5
  • Fluvoxamine
  • Cimetidine
  • Quinolones
  • Rifampicin
  • Oestrogens
  • Carbamazepine
  • Adrenergic agonists & antagonists
  • Opiate agonists & antoagonists
  • Prostaglandin inhibitors
  • Antidepressants
  • Tryptophan
  • Benzodiazepines
  • Hypnotics
  • Thioridazine
  • Imipramine
6

Please use a minimum of 1 words.

7
  • Smoking may decrease the effects of melatnonin and should be avoided during treatment
  • You shouldn't drink alcohol whilst taking melatonin
  • You should avoid driving or operating machinery whilst taking melatonin as it can make you drowsy
  • You should only take melatonin around 1-2 hours before you go to bed
  • Melatonin is only for the short-term treatment of primary insomnia. 
8

Please use a minimum of 1 words.

9

After an initial 13 weeks taking Circadin, you must take a break from the medication for at least 28 days before taking it again. This is to see whether you can return to a normal sleeping pattern without the use of melatonin supplements.

10
You have an allergy to melatonin You've used this treatment in the past and suffered with serious side effects You're using melatonin to treat long-term insomnia
Online consulting and prescribing service
Dispensing of prescriptions and supply of medicine
Secure SSL Encryption

Circadin

Circadin is a natural alternative to other sleeping pills such as zolpidem and zopiclone, as it contains a synthetic version of melatonin, a naturally occurring hormone. Circadin helps your body to adjust to its internal clock, regulating sleep/wake cycles and allowing you to get a restful night’s sleep.

Circadin is typically prescribed for short-term primary insomnia, as well as jet lag in patients that have crossed through time zones. The drug helps to raise levels of melatonin in patients who don’t produce enough of it to fall asleep, and should be taken after food, around 2 hours before bedtime.

Circadin gets its name from something called the circadian rhythm – a 24 hour cycle that occurs in all living beings and affects sleep and wakefulness. If there isn’t enough melatonin being produced, it can affect the body’s natural circadian rhythm, meaning that getting to sleep can be more difficult, so Circadin tablets help to restore it – encouraging your body to relax.

Melatonin tablets

Circadin comes in the form of 2mg melatonin tablets. Melatonin tablets should be swallowed whole with a glass of water after the last meal of the day.

Usually, melatonin is produced by the pineal gland above the brain, and is influenced by outside factors such as light and dark. When it goes dark at night, your eyes send a signal to your brain, telling it that it’s time to feel tired. The brain then stimulates the release of melatonin from the pineal gland. Whilst it isn’t entirely understood exactly how melatonin works, it’s thought to promote sleep by relaxing your body and preparing it for rest. For example, once melatonin is released, it binds to receptors in your body that help you to relax, such as reducing nerve activity and dopamine levels, making you feel more tired.

When the sun rises in the morning, your eyes detect the light and send a signal to the brain telling it that it’s time to wake up. In turn, melatonin levels fall and you should wake up feeling rested and ready for the day ahead.

However, there are some people that don’t produce enough melatonin, meaning that it’s difficult for their bodies to enter a relaxed state, which is where melatonin tablets can help.

Melatonin tablets boost levels of the “sleep hormone” in the body shortly after it’s taken, so it’s important to make sure you take a dose around 2 hours before you plan to go to bed. Melatonin is generally produced naturally in dark or dimly lit environments. So taking it at night will boost your normal levels to help you fall asleep faster.

Modern life can affect your circadian rhythm and therefore how much melatonin your body produces. For example, stress, shift work, and blue light from electronics can all contribute to lower than optimal melatonin levels, contributing to symptoms of insomnia and restlessness at night. Melatonin tablets can help to relieve these symptoms, but it’s always a good idea to use them in conjunction with good sleep hygiene. Some methods you can try to naturally encourage your body to adjust to its internal clock include:

  • Limiting day time naps
  • Not eating fatty or spicy foods before bed
  • Exercising before bed
  • Ensuring adequate exposure to natural light
  • Reducing caffeine intake during the day
  • Not using electronics in the same room that you sleep in

Making sure you help yourself with as many of these tips as possible will ensure that the melatonin tablets work to their full potential.

Circadin 2mg

Circadin is only available in a 2mg dose. This is the recommended daily amount for treating short-term primary insomnia, and you should start on this dose to see if it works for you.

Before you take Circadin 2mg tablets, you should make sure you read the patient information leaflet thoroughly to make sure you know everything you need to about using melatonin supplements.

Circadin 2mg should be taken after the last meal of the day, around 2 hours before you go to bed. If you feel as though one tablet isn’t giving you the results you’d hoped for, and that you’re still struggling to sleep, your own GP may recommend increasing the dose to 2mg tablets taken together at the same time. You should not exceed the maximum dose of 4mg per day, and you must speak to your own GP before increasing your dose on your own.

Is Melatonin safe?

Melatonin is perfectly safe for a vast majority of people. Due to the fact that it’s a synthetic version of a naturally occurring hormone, most people are able to take it without any problems. However, as with any prescription medicine, there are some people that need to take caution and either speak to their GP before considering buying melatonin, or should avoid the drug completely.

If you fall into any of the below categories, please make an appointment with your own GP before you buy melatonin online:

  • People with liver problems
  • People with kidney problems
  • People that are intolerant to some sugars
  • People with an autoimmune disease
  • Smokers

As well as these conditions, there are certain medicines that can interact with Circadin, meaning that it may not be safe for you if you’re already taking any of the following:

Fluvoxamine
Psoralens
Cimetidine
Quinolones
Rifampicin
Oestrogens
Carbamazepine
Andrenergic agonists/antagonists
Opiate agonists/antagonists
Prostaglandin inhibitors (NSAIDs)
Antidepressants
Tryptophan
Alcohol
Benzodiazepines
Non-benzodiazepine hypnotics
Thioridazine
Imipramine

If you recognise any of the drugs on this list as ones that you already take, you should also make an appointment with your GP to discuss the suitability of melatonin tablets for sleep. You may still be able to take them with a dosage adjustment to one of your other medicines. However, you shouldn’t make this decision without the guidance of a doctor.

If you aren’t sure if you take any of these medicines, write down a list of everything you do take and ask your local pharmacist to check if any of them interact with Circadin or melatonin tablets.

If you don’t have any of the conditions mentioned above, and don’t take any of the medicines on the list, melatonin pills should be a safe option to treat your insomnia.

Melatonin side effects

Despite the fact that melatonin is a naturally occurring hormone, it doesn’t always come without side effects. However, not everybody experiences these, and many find that the benefits outweigh any symptoms that they experience relating to Circadin. Some of the most commonly reported side effects of melatonin include:

Irritability
Insomnia
Anxiety
Lethargy
High blood pressure
Mouth ulcers
Inflamed skin
Rash
Nervousness
Abnormal dreams
Migraine
Dizziness
Indigestion
Dry mouth
Night sweats
Dry skin
Restlessness
Nightmares
Headache
Tiredness
Abdominal pain
Nausea
Itching
Feeling weak

Whilst the side effects may look off-putting or alarming, a vast majority of them were classified as “uncommon” or “rare” (affecting up to 1 in 100, or 1 in 1000 people respectively).

There are also some more serious side effects that have occasionally been associated with the use of Circadin 2mg. If you experience any of the following, make an urgent appointment to see your doctor, or ring 999 and state that you’ve taken melatonin:

  • Chest pain
  • Loss of consciousness
  • Feeling your heart beat
  • Depression
  • Visual disturbances
  • Vertigo
  • Blood in urine
  • Reduced white blood cells
  • Reduced blood platelets
  • Psoriasis

Melatonin UK

Melatonin in the UK is only licenced to treat short-term insomnia in patients over the age of 55. However, it’s commonly used amongst other age groups for sleeping problems including insomnia and jet lag. Due to the way that melatonin works, many patients struggling with sleep problems have found that melatonin helps to regulate their internal clock, allowing them to get a full, restful night’s sleep.

Melatonin is a natural alternative to sedative medications such as zopiclone and zolpidem, making it a popular choice for many that struggle with falling asleep at night. Circadin/melatonin in the UK is available from your doctor as well as online from trusted prescribers such as Doctor4U.

Melatonin NHS

Melatonin is available on the NHS for patients that suffer with short-term primary insomnia who are over the age of 55. If you don’t fall into these categories, you may find it difficult to obtain Circadin from your NHS GP. However, if you feel as though you need it and your doctor agrees that it’s a suitable treatment, they may prescribe it to you on a short-term basis and monitor your condition whilst you take it.

Buy melatonin UK

You can buy melatonin in the UK either from a private doctor, or through an online prescribing service such as Doctor4U. Whilst you may feel nervous about ordering medicines from the internet, it couldn’t be safer or easier to buy melatonin through us. If you feel that this is the right treatment for you, simply complete a consultation form for insomnia and choose your treatment at the end.

One of our doctors will review your answers and determine whether Circadin is the right treatment for you. If it is, your order will be shipped to you in discreet packing either through royal mail or DPD (whoever postal method you’ve chosen).

When you buy melatonin online in the UK, you should always look for a clickable logo that says “click to verify if this website is operating legally”. Ours can be found in the footer of our website on every page. This should take you to our registration page with the MHRA (the governing body for medicines and healthcare products in the UK). We’re proud to display ours as it means we work to the highest possible standards, and you can be assured confidentiality and safety.

Advice on Addiction and Medication Restrictions

If you are at all worried or concerned about an addiction to any type of medication, we urge you to speak to a professional for help and advice. Below are links to organisations that can help.

  • Talk To Frank

  • NHS Help & Advice On Drug Addiction
  • Dosage Instructions
    Take ONE tablet once each night 1-2 hours before bedtime. 13-week treatment.
    https://www.chemist-4-u.com/circadin-pr?utm_source=d4u&utm_medium=refferal&utm_campaign=d4u-pdp
    Active ingredient: Melatonin
    Write Your Own Review
    You're reviewing:Circadin PR
    No Questions
    Circadin PR Dosage Quantity Cost Including Consultation
    Circadin 2mg 30 Tablets £31.99
    Circadin 2mg 60 Tablets £56.99
    Circadin 2mg 90 Tablets £81.99

    Delivery Charges

    The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

    UK Standard Delivery, £1.99

    Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

    standard UK delivery within 3-5 working days

    Additional terms and conditions apply.

    UK Express Delivery, £2.99

    Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

    If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

    Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, £14.99

    Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply

    DPD Saturday Delivery, by 12:00am, £21.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, by 10:30am, £29.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply, please see below.

    US and outside the UK

    Unfortunately, we can't process orders from outside the UK at this time.


    Terms and Conditions

    Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

    All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

    Active ingredient: Melatonin
    Out of stock