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Differin

Differin is a medicine used as a treatment for acne symptoms. It can come in the form of either a white cream or gel, but in either form the method for using it is the same. When applied to relevant areas of the skin, this treatment prevents the blockage of oil the skin naturally produces to keep itself moisturised.

Prices start from £29.99 for 1 pack


Last Patient Information Review: 08/03/2019

    Differin Cream Patient Information Leaflet


    Differin Gel Patient Information Leaflet

    £ 29.99 InStock
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    • If you use other treatments alongside adapalene/Differin, they should be applied at different times of the day. For example, applying the other treatments in the morning and adapalene/Differin at night.
    • If you find that your skin becomes more sensitive or irritated whilst using adapalene or Differin, you should alternate the nights that you use it, or stop applying it for a while.
    • Adapalene/Differin shouldn't be used by pregnant women, as it may harm the foetus. If you're a woman that is capable of having children, you should use contraception.
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    • You have an allergy to adapalene or Differin
    • You've used medications containing adapalene in the past and suffered with serious side effects
    • You're already using adapalene or Differin to treat a condition other than acne
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    What is Differin?

    Differin is a treatment for acne symptoms that can come in the forms of either a cream or a gel. It contains vitamin A and helps to prevent spots by unblocking pores and promoting skin cell renewal.

    This treatment can be used on the face, chest or back for acne, where the skin may have lots of spots, pimples and blackheads. The body absorbs Differin in very small amounts and has little effect, except on the surface of the skin.

    How does Differin work?

    Differin contains an ingredient called adapalene which creates an anti-inflammatory effect to reduce soreness and irritation. When the cream or gel is applied to skin showing acne symptoms, the adapalene reduces the production of keratin skin cells which ordinarily clog up pores.

    When sebaceous glands become blocked on parts of the skin, this leads to a build of sebum (the oil the skin produces to keep it moisturised), which can eventually lead to black or whiteheads being formed and later an infection or cyst. But with keratin skin cells removed, the sebum can instead exit the sebaceous cells and stop spots from forming.

    How do I use Differin?

    Differin is meant to be used at night shortly before going to bed. The area of skin where the cream or gel will be applied should be clean and dry before treatment. A thin film of the cream/gel is put on the affected areas with your fingertips and rubbed in gently. How long you will use this treatment for depends on how quickly your condition improves. If you’ve used this medicine for three months or longer, then it’s important to see your doctor so they can check how your condition has improved.

    When Differin is in use, avoid exposure to sunlight and artificial UV light. Avoid applying the cream/gel to the eyes, mouth or nostrils. If accidental contact in these areas does occur, immediately wash with warm water.

    What are the side effects of Differin?

    There are several side effects that could be experienced while taking Differin in either gel or cream form. The most commonly reported issues include the following:

    • Dry skin
    • Irritation of the skin
    • Burning sensation on the skin
    • Redness of the skin (erythema)

    Other side effects are much more uncommon, but the following all have some possibility of occurring while using this treatment:

    • Local skin reaction
    • Sunburn
    • Skin discomfort
    • Itchy skin
    • Peeling skin
    • Allergic contact reaction
    • Pain or swelling of the skin
    • Irritation or swelling around the eyelids

    It’s best to talk to your doctor or pharmacist if you experience any side effects (whether they’re listed here or not) that cause a great deal of discomfort.

    Can I use Differin?

    Differin gel and cream are only intended for use on adults and adolescents aged 12 years and over. If you are pregnant or planning a pregnancy, then you should avoid using this medication. It should also be avoided if you have a skin condition called eczema.

    This medicine is not designed for areas of skin where there are cuts or scrapes. An alternative treatment is better for dealing with these. If you are using any other acne products (containing benzoyl peroxide, erythromycin or clindamycin) at the time you want to use Differin, then you should be ok to use it but any other treatments should be applied in the morning, while Differing is used at night.

    What if I apply too much Differin to the skin?

    If you apply more of this treatment than necessary, it will not get rid of your acne at a faster rate but it does make side effects more likely. Most likely your skin can become irritated and red and some peeling could also occur.

    How should Differin be stored?

    Whether it’s in cream or gel form, this medication should be kept in its original container and stored somewhere that’s not above 25 degrees centigrade. This product is not to be frozen. Like with other medicines, it should be kept out of the sight and reach of children.

    What if I forget to use Differin?

    If you forget to use this medication on one night, then it should not create any issues so there’s no need to worry. When you remember you’re meant to be using Differin, just start using it again in the same way as before, at the appropriate time of night.

    How is my order shipped to me?

    When an order is ready for shipping, it is collected and delivered by either the Royal Mail or DPD depending on your preference (or possibly your location or the item you ordered). Each order is assigned a tracking number, which will be emailed to you at the time of dispatch. Your medicine will be sent in plain and discreet packaging that’s eco-friendly. We do not include any branding on our packaging nor any labels which inform readers what type of product is contained within.

    Advice on Addiction and Medication Restrictions

    If you are at all worried or concerned about an addiction to any type of medication, we urge you to speak to a professional for help and advice. Below are links to organisations that can help.

  • Talk To Frank

  • NHS Help & Advice On Drug Addiction
  • Dosage Instructions
    Apply ONCE daily, thinly to the affected area(s).
    https://www.chemist-4-u.com/differin
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    Differin Dosage Quantity Cost Including Consultation
    Differin 0.1% Cream 1 Pack £29.99
    Differin 0.1% Cream 2 Pack £49.99
    Differin 0.1% Gel 1 Pack £29.99
    Differin 0.1% Gel 2 Pack £49.99

    Delivery Charges

    The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

    UK Standard Delivery, £1.99

    Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

    standard UK delivery within 3-5 working days

    Additional terms and conditions apply.

    UK Express Delivery, £2.99

    Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

    If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

    Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, £14.99

    Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply

    DPD Saturday Delivery, by 12:00am, £21.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, by 10:30am, £29.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply, please see below.

    US and outside the UK

    Unfortunately, we can't process orders from outside the UK at this time.


    Terms and Conditions

    Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

    All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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