UK icon
UK Registered Pharmacy
head shoulders icon
Friendly Patient Support
padlocks icon
Confidential Service

duloxetine

Duloxetine capsules are popularly used to treat neuropathic pain and can be prescribed as treatment for a variety of other conditions related to either physical pain or mental disorders. This medicine adjusts certain substances in the nervous system in order to reduce pain signals and improve the patient’s mental balance.



Duloxetine Capsules Patient Information Leaflet

Last Patient Information Leaflet Review: 24/01/2020



This medicine is no longer available to request via our online service. If you are still having trouble with your symptoms please visit the NHS website for services in your area.


Price Checker:


For delivery by
Order within:
Next Day delivery also available

Online consulting and prescribing service
Dispensing of prescriptions and supply of medicine
Secure SSL Encryption

Dr. Diana Gall GMC No. 7685129

Dr Diana Gall graduated from medical school in 2005 and has since undertaken further intensive training in many different areas of medicine. Dr Diana has reached consultant level and has practiced medicine all over Europe.

Shamir Patel GPHC No. 2049338

Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Duloxetine?

Duloxetine is a medication that can be taken to treat various conditions including diabetic neuropathic pain, bone or muscle pain, fibromyalgia, and generalised anxiety disorder. It may also be used to treat chronic back pain or arthritis. As well as being able to reduce pain, this medication can potentially alter and improve your mood, appetite and energy levels.

How does Duloxetine work?

Duloxetine increases the levels of serotonin and noradrenaline in the nervous system. These substances naturally occur in the brain and they help to maintain mental balance and prevent the movement of pain signals in the brain. This treatment belongs to a class of medications known as selective serotonin and norepinephrine reuptake inhibitors or SNRIs for short.

How do I take Duloxetine?

The exact daily dosage and duration of treatment with Duloxetine will depend on what condition you are treating. Your doctor or pharmacist will guide you on how to take this medicine, which strength of capsules to use and for how long they should be taken. When taking these capsules, they should be swallowed whole (preferably with a drink of water). The capsules should not be crushed or chewed.

When treating diabetic neuropathic pain or depression, the usual dose is 60mg once a day. When treating generalised anxiety disorder, the usual starting dose is 30mg once a day. The daily dosage may go up to 60mg or 120mg later on, depending on your doctor’s judgement on what is right for you. It is advisable to take these capsules around the same time each day, so it is easier to remember keeping up with your treatment.

What are the side effects of Duloxetine?

You may not experience any side effects while using Duloxetine, but some are possible and certain side effects are more commonly reported than others. The most commonly reported side effects include headaches, feeling sleepy, nausea and having a dry mouth. Other common side effects reported include the following:

  • Lack of appetite
  • Trouble sleeping
  • Feeling agitated
  • Less sex drive
  • Anxiety
  • Unusual dreams
  • Dizziness
  • Feeling sluggish
  • Numbness
  • Difficulty or inability to experience orgasm
  • Blurred eyesight
  • Tinnitus
  • Feeling the heart pumping in the chest
  • Increased blood pressure and flushing
  • Increased yawning
  • Constipation
  • Diarrhoea
  • Vomiting
  • Heartburn or indigestion
  • Increased sweating plus possibly a rash
  • Muscle pain and spasms
  • Frequent and/or painful urination
  • Problems getting an erection
  • Weight loss

Other side effects are possible but also far less common. If you experience any side effects that are particularly troubling, contact your doctor, pharmacist or nearest hospital emergency department for support.

Can I use Duloxetine?

Check before using Duloxetine that you do not have any health-related circumstances that make taking this medication ill-advised. You should not use this treatment if any of the following applies to you:

  • You have a liver disease
  • You have severe kidney disease (check with your doctor if unsure)
  • You are taking or have taken within the last 14 days a medicine known as a monoamine oxidase inhibitor (MAOI)
  • You are taking fluvoxamine, usually used to treat depression
  • You are taking ciprofloxacin or enoxacin (to treat certain infections)
  • You are taking any medicines that contain duloxetine

You should speak to your doctor about any conditions you have or medicine you’re taking, even if they are not listed above. Other circumstances may prohibit you from using Duloxetine safely, but your doctor will make that judgement by assessing you. The following may prevent you from using this medication but will depend on your doctor’s assessment:

  • You are taking an herbal treatment known as St. John’s Wort
  • You have a kidney disease
  • You have experienced seizures and/or mania in the past
  • You suffer from bipolar disorder
  • You have eye problems, such as certain kinds of glaucoma
  • You have a history of bleeding disorders
  • You are at risk of low sodium levels
  • You are currently being treated with a medicine that could cause liver damage
  • You are taking another medicine that contains duloxetine as an ingredient

What is the minimum age for taking Duloxetine?

Duloxetine tablets are normally taken only by adults aged 18 years old or above. They are typically not deemed suitable for children and adolescents and if any were to take this type of medication, they face an increased risk of certain side-effects such as suicidal thoughts and hostility.

However, in rare cases, a doctor may prescribe Duloxetine to someone aged under 18 if they decide it is in the patient’s best interests. If a family member aged below 18 is prescribed this treatment, inform your doctor if any symptoms mentioned previously develop or worsen. The long-term safety effects concerning growth, maturation, and cognitive and behavioural development of duloxetine in this age group have not yet been demonstrated.

What if I take too much Duloxetine?

If you take a larger dose of this medication than you were meant to, you should call your doctor or pharmacist immediately for advice. You may experience some symptoms as a result of overdosing. These can include the following:

  • Sleepiness
  • Coma
  • Fits
  • Vomiting
  • Fast heart rate
  • A rare reaction called serotonin syndrome which can cause feelings of great happiness, drowsiness, clumsiness, restlessness, fever, sweating, rigid muscles and feelings similar to being drunk

What if I forget to take Duloxetine?

If you miss a dose of this medication, then take it as soon as you remember, unless it is just before your next one is due. If your next dose is due, then skip the one you forgot about and take only a single dose as usual at the normal time. Never take a double dose to make up for a forgotten dose. If you wish to stop taking this medication, then speak to your doctor for advice so they can determine if you can stop using Duloxetine and when.

Dosage Instructions
No
Write Your Own Review
You're reviewing:duloxetine
No Questions

Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

Additional terms and conditions apply.

UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply

DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply, please see below.

US and outside the UK

Unfortunately, we can't process orders from outside the UK at this time.


Terms and Conditions

Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

Out of stock