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Flurbiprofen

Flurbiprofen is a type of painkiller that belongs to the NSAID family (non-steroidal anti-inflammatory drug). It works in a similar way to ibuprofen, naproxen and diclofenac. Flurbiprofen is prescribed to treat symptoms of pain and inflammation, often for chronic conditions such as arthritis, but it can also be given for short-term inflammatory pain such as dysmenorrhoea and toothache, as well as postoperative pain.

Flurbiprofen, along with other NSAIDs, have been known to slightly increase your risk of heart attack. If you or anyone in your family have been diagnosed with heart problems, you should see your own GP before ordering this medication to make sure it’s safe for you to take.

Last PIL Review Date: 27/01/2020

See Flurbiprofen Patient Information Leaflet

This medicine is not available to request via our online service. If you are still having trouble with your symptoms please visit the NHS website for services in your area.

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  • Lithium
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  • Methotrexate
  • Ciclosporin
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  • Corticosteroids
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  • Other NSAIDs or anti-inflammatory drugs
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  • Allergy to flurbiprofen
  • History of stomach or duodenal ulcer
  • Inflammatory bowel disease such as Crohn's or ulcerative colitis
  • History of bleeding in the stomach or intestine
  • Asthma
  • History of breathing difficulties associated with using NSAIDs
  • Pregnant
  • Heart, liver or kidney failure
  • Current acute dehydration
  • Systemic lupus erythematosus
  • Liver or kidney disease
  • Any heart problems, or at risk of developing heart problems
  • History of stroke
  • Blood clotting disorder
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You have an allergy to flurbiprofen

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You're already using a treatment that contains flurbiprofen for any reason other than pain relief

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What is flurbiprofen?

Flurbiprofen is a type of NSAID (non-steroidal anti-inflammatory drug) that’s prescribed to treat pain and inflammation. In some cases, these conditions may be chronic. In other cases, the patient may only need to take the drug for a few days. Some of the conditions flurbiprofen is indicated for include:

  • Osteoarthritis
  • Rheumatoid disease
  • Ankylosing spondylitis
  • Swollen joints
  • Frozen shoulder
  • Bursitis
  • Tendinitis
  • Tenosynovitis
  • Low back pain
  • Sprains
  • Strains
  • Dysmenorrhoea
  • Toothache
  • Post-operative pain
  • Migraine

The dosage you’re prescribed will depend on your condition and the severity of your symptoms.

Flurbiprofen is part of the same family of medications as naproxen, diclofenac, celebrex and ibuprofen.

How does flurbiprofen work?

In certain painful inflammatory conditions, the body releases compounds called prostaglandins in response to tissue damage, infection, or disease. These contribute to the pain and inflammation that you feel when you have a condition such as the ones listed above.

Flurbiprofen blocks an enzyme that’s responsible for producing these prostaglandins, and therefore reduces the amount of them in your body. This then helps to relieve your symptoms of pain and inflammation, helping you to live your day-to-day life more easily.

Can I take flurbiprofen?

Flurbiprofen and other NSAIDs can cause increase your risk of developing some health issues , so anybody using them should take care. However, there are some people that will need to be more cautious than others due to pre-existing conditions that might make it dangerous to take NSAIDs. IF you’ve been diagnosed with any of the following, you should completely avoid taking flurbiprofen until you’ve spoken to your own doctor first:

  • Allergic to flurbiprofen or any ingredients
  • History of stomach ulcer
  • History of ulcerative colitis
  • Crohn’s disease
  • Asthma
  • Previous allergy to other NSAIDs
  • Being in the last trimester of pregnancy
  • Severe heart failure
  • Kidney failure
  • Liver failure
  • Acute dehydration
  • Breast feeding
  • Systemic lupus erythematosus (SLE)
  • Liver disease
  • Kidney disease
  • Any heart problems
  • High blood pressure
  • Diabetes
  • High cholesterol
  • Smoking
  • Blood clotting disorder
  • Intolerance to some sugars

Taking flurbiprofen if you have any of these conditions might not be the best thing for you. In this case, your doctor might prescribe an alternative medication, give you a lower dose, or want to monitor you more closely.

Does flurbiprofen interact with any other medicines?

Yes. Like most medications, there are some interactions that you should be aware of, and if you know you’re taking any of the following, you should discuss the best course of action with your GP:

  • Diuretics
  • Cardiac glycosides
  • ACE inhibitors
  • Anticoagulants
  • Lithium
  • Zidovudine
  • Ciclosporin
  • Tacrolimus
  • Corticosteroids
  • SSRI anti-depressants
  • Quinolone antibiotics
  • Mifepristone
  • Any other anti-inflammatory painkillers including aspirin and COX-2 inhibitors

If you’re not sure whether you’re taking any of these medicines, pop in to your local pharmacy with a list of what you already take, and they should be able to tell you if they fall into any of the above categories. Depending on your dosage, you might still be able to take flurbiprofen, or you might be offered an alternative anti-inflammatory.

What are the side effects of flurbiprofen?

There are barely any drugs that come without the risk of side effects, and flurbiprofen is no exception. All of the potential side effects are listed in the patient information leaflet (PIL) that comes with the medication, but we also want to make you aware of some critical symptoms as well as some of the most common complaints that people have reported while taking flurbiprofen.

The following group of side effects and symptoms require emergency treatment. If you experience any of them, you should go to your nearest A&E department:

  • Severe headache, a temperature of 38 celsius or above, stiff neck, intolerance to light
  • Blood in faeces
  • Black, tarry stools
  • Vomiting blood or bits that look like coffee grounds
  • Allergic reaction
  • Unexplained stomach pain or other gastrointestinal issues
  • Increased bruising, fever, sore throat, fatigue and increased infections
  • Jaundice
  • Fatigue, swelling of the face, abdomen, thighs or ankles, difficulty urinating, back pain
  • Severe headache, visual disturbances

If you’re unsure whether you’re experiencing any of the above symptoms, or don’t know how serious it is, you should call NHS 111, a 24/7 service that can provide medical advice and urgent or out-of-hours appointments. You should state that you’ve taken flurbiprofen and may be experiencing side effects.

You may also experience milder side effects which are more common, and whilst they might be unpleasant, they aren’t as concerning as the symptoms listed above. However, you should always report any side effects to your doctor, and also via the MHRA yellow card app. Some of the most common symptoms associated with using flurbiprofen include:

  • Headache
  • Dizziness
  • Indigestion
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Wind
  • Tiredness
  • Generally feeling unwell
  • Raised levels of liver enzymes in the blood
  • Fluid retention
  • Anaemia
  • Tingling/numbness in the hands and feet
  • Tinnitus
  • Unexpected photosensitivity
  • Vertigo
  • Asthma
  • Mouth ulcers
  • Stomach and lower gut ulcers
  • Gastritis

More side effects (including rare and uncommon ones) are listed in the patient information leaflet, so it’s important that you read it thoroughly before taking flurbiprofen so you’re aware of all of the risks.

It’s important to know that using NSAIDs can slightly increase your risk of heart attack. This risk is further increased if you take them for a long time. Whilst flurbiprofen is often used as a long-term treatment, you should inform your doctor as they may want to monitor you more closely.

Will flurbiprofen give me a stomach ulcer?

NSAIDs can increase your risk of developing a stomach ulcer, so to minimise this, we advise that you take your pills along with some food. Taking medicine such as this on an empty stomach makes it more likely to cause gastrointestinal problems.

There’s no guarantee that you’ll develop a stomach ulcer, but erring on the side of caution and taking it with a meal or a snack is a great option to avoid the risk as much as you can.

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The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

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Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

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Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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