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Diabetes

Janumet

Janumet contains sitagliptin and metformin, and is used to control high blood sugar in people with type two diabetes.

The combined medication has been proven to be more effective at lowering levels of blood glucose than just one of the drugs alone, and has even shown to promote weight loss in patients with a high BMI.

Janumet can only be used to treat type 2 diabetes, and not other conditions such as PCOS or type 1 diabetes, as there are more appropriate treatments for these.

You may benefit from taking Janumet if your blood sugar levels are high and you have a BMI of over 35. It can be taken alongside other medications for diabetes as long as they don’t contain the same ingredients as Janumet as this can cause an overdose.

The drug works more effectively when used in conjunction with a healthy diet and exercise, and shouldn’t be treated as a substitute for these lifestyle changes.

Last PIL Review Date: 21/01/2020

See Janumet Patient Information Leaflet

This medicine is not available to request via our online service. If you are still having trouble with your symptoms please visit the NHS website for services in your area.


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Dr. Diana Gall GMC No. 7685129

Dr Diana Gall graduated from medical school in 2005 and has since undertaken further intensive training in many different areas of medicine. Dr Diana has reached consultant level and has practiced medicine all over Europe.

Shamir Patel GPHC No. 2049338

Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Janumet?

Janumet is used to treat type 2 diabetes by reducing the amount of glucose in the blood. It contains two active ingredients: metformin and sitagliptin.

It’s been proven to be more effective than metformin alone, and has even shown to stimulate weight loss in patients with a high BMI.

How does Janumet work?

Janumet’s 2 ingredients both help to lower blood sugar.

Metformin works by reducing the amount of glucose released by the liver, and also increases insulin sensitivity.

Sitagliptin on the other hand increases the amount of incretins that your body releases, which stimulates the production of insulin.

This is why the medicine is more effective than just one of the generic drugs used alone, as it’s fighting high blood sugar with a double edged sword.

Unlike metformin, Janumet isn’t also used to treat polycystic ovary syndrome (PCOS) – it’s only ever used to treat type 2 diabetes.

It’s important to know that Janumet isn’t a substitute for a healthy diet and exercise, in fact, it should be used alongside these lifestyle changes so it can reach its full potential.

Will Janumet make me gain weight?

No, in fact, it’s been shown to do the opposite. Whilst Janumet isn’t a weight loss drug, the way it works can stimulate weight loss in patients with a high BMI. The medicine also affects the brain, helping you to feel fuller for longer and you may actually notice a reduced appetite.

Can Janumet cause low blood sugar (hypoglycaemia)?

When used on its own to treat diabetes, Janumet shouldn’t cause hypoglycaemia. However, if you’re taking other medications to manage your diabetes such as insulin, the risk of low blood sugar might be increased. It’s important to know the symptoms of hypoglycaemia just in case it happens to you:

Fatigue
Dizziness
Pale skin
Shakiness
Headaches
Anxiety
Sweating
Hunger
Irritability
Visual disturbances
Seizures
Loss of consciousness
Weakness
Fast heartbeat (tachycardia)

What are the side effects of Janumet?

Janumet, like all medicines, can cause side effects. Although these are usually mild, they may be uncomfortable. However, the good news is that if you do experience any side effects, they normally disappear within a few weeks of treatment. Here’s what to look out for:

Signs of infection
Nausea and vomiting
Headache
Diarrhoea
Joint pain
Muscle aches
Arm or leg pain
Back pain
Itching
Blisters
Constipation
Kidney problems

Although some of the symptoms on this list might look alarming, some of them are incredibly rare. The most common side effects are nausea, diarrhoea and constipation, and these are the ones that usually subside soon after you begin treatment.

Due to the metformin in Janumet, there’s a chance it could cause a rare condition called lactic acidosis. The symptoms to look out for are:

Extreme fatigue
Nausea
Vomiting
Loss of appetite
Muscle pain
Difficulty breathing

If you notice any of these, it’s a medical emergency that could potentially be fatal. Please stop taking the medicine and seek urgent care by calling 999.

Can I take Janumet?

Most people are able to take Janumet for type 2 diabetes, but you should completely avoid the medicine if you have:

  • An allergy to any of the ingredients
  • Severe kidney disease
  • Diabetic ketoacidosis

In some circumstances, you may still be able to take the medication under the circumstance that you tell your GP. If you have any of the following medical conditions, please speak to your GP before starting Janumet:

Kidney disease
Liver disease
Heart disease
Pancreatitis
High triglycerides
Gallstones
Alcoholism
Pregnancy

You should also temporarily stop taking Janumet if you’re due to have a procedure that involves being injected with contrast dye (such as a CT or MRI scan).

How do you take Janumet?

Janumet comes in either tablet form, and both should be swallowed whole with a glass of water and a meal.

Most people take the medication twice a day, and it might help to take it with breakfast and dinner to make it part of your daily routine and so that you associate it with a meal.

When you first start taking Janumet, it’s a good idea to slowly increase your dosage over a period of a few weeks as this can minimise the risk of experiencing side effects. This is also the reason that the drug is taken with food, as this can lower the gastrointestinal side effects you might feel.

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Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

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UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

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Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

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Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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