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Lariam is a medicine that is used to help prevent and treat malaria. It contains the active ingredient mefloquine, which is an antimalarial agent.

See Lariam Anti-Malarial Tablets Patient Information Leaflet

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Lariam (Mefloquine) Anti-Malarial Tablets
  • Atovaquone or Proguanil Chloride (Malarone)
  • Doxycycline Mefloquine (Lariam)
  • Quinine or Quinidine Chloroquine
  • Any antibiotics

You can confirm this by checking the NHS fitfortravel website

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  • You will read the Patient Information Leaflet supplied with your medication
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Lariam is a medicine that is used to help prevent and treat malaria. It contains the active ingredient mefloquine, which is an antimalarial agent.

See Lariam Anti-Malarial Tablets Patient Information Leaflet


What is Lariam and what does it do?

Lariam is a medicine that is used to help prevent and treat malaria. It contains the active ingredient mefloquine, which is a antimalarial agent.

Malaria is a disease that spreads to humans via mosquitoes. The mosquitoes pass on the parasite by biting. When Malarone is taken to prevent Malaria, the active ingredients in the treatment kills off the parasites before they cause illness.

When is Lariam prescribed?

Lariam can be prescribed to help prevent Malaria when visiting malaria risk areas. These areas include, but are not limited to many parts of Africa and Asia, Central and South America and certain areas of the Middle East.

No antimalarial treatment gives complete protection against Malaria, so it is important that you also take other preventative measures to decrease the risk as much as possible. Always use mosquito repellent and clothing to protect yourself and if possible a mosquito net at night.

To find our whether the country you are visiting belongs to any of the Malaria risk areas, visit the NHS Fit for Travel website

Is Lariam suitable for my condition?

The suitability of this medicine will be assessed by our doctors. Lariam may be suitable for you if you are travelling to a malaria risk area, are not allergic to mefloquine and don’t have severe liver problems.

You must inform our doctors via the medical questionnaire if any of the below applies to you:

  • If you currently or previously have experienced depression, thoughts about suicide or self-endangering behaviour.
  • If you currently or previously have experienced any other mental problem, such as anxiety disorder, schizophrenia or psychosis.
  • If you have previously experienced seizures or convulsions.
  • If you are taking any other medicines, including halofantrine, ketoconazole, efavirenz, tramadol, antihistamines, medicines to treat heart problems, anti-depressants, medicines to treat epilepsy or medicines for blood clotting disorders.

There may be other medicines and conditions that affect the suitability of Lariam. It is therefore important that you read the patient information leaflet before use.

What is the recommended dosage of Lariam?

You should follow the doctor’s instructions on how to take this medicine. The doses outlined below is for your reference only. The tablets should be swallowed whole with plenty of water, preferably after a meal.

Never exceed the stated dose.

Lariam doses for preventing malaria

Take 1 tablet once a week. Always take the tablet on the same weekday.

The first tablet should be taken 10 days before you travel. The second tablet is taken 3 days before you leave.

Continue to take the tablets on the same weekday throughout the duration of your stay. You must continue taking the tablet for 4 weeks after your return to a malaria free area.

For a 2 week holiday, a pack of 8 tablets will help to prevent you from catching malaria. The table below indicates the quantity required for a 2, 4 and 6 week holiday.

Travel DurationLariam Start DateLariam Finish DateLariam Tablet Quantity
2 Weeks 10 Days Before Departure 4 Weeks after Returning 8 Tablets
4 Weeks 10 Days Before Departure 4 Weeks after Returning 10 Tablets
6 Weeks 10 Days Before Departure 4 Weeks after Returning 12 Tablets

Does Lariam cause any side effects?

Yes, just like all medicines Lariam may cause side effects. However, the susceptibility to side effects varies from one person to another and not everyone will get them.

It is important that you read through the patient information leaflet before use so that you know how to recognise side effects and when to seek medical advice.

Common side effects associated with taking Lariam include:

  • Depression.
  • Anxiety.
  • Sleeping problems (sleepiness, unable to sleep).
  • Dizziness.
  • Headache

Please note, the above side effects are not a complete list. You can find more information about side effects in the patient information leaflet.

Contact your GP immediately if you notice a change in your mental status or any signs of an allergic reaction, such as difficulty breathing, sudden swelling of the face, lips or tongue, rash or itching.

Can I reduce the risk of getting side effects?

Yes, you can decrease the risk of side effects by reading the patient information leaflet before use. This will tell you whether there are any other medicines that are likely to interact with Lariam and potentially cause side effects.

Below are a couple of other things you can do:

  • While filling in the medical questionnaire, remember to include any other medicines you are taking. Don’t forget to also include over the counter medication and supplements.
  • Take Lariam with food or a milky drink if you experience stomach upset.
  • Always take Lariam on the same weekday.

How do I buy Lariam online?

To legally and safely buy doxycycline online you need a prescription from a GMC (General Medical Council) registered doctor. Our online doctor service allows you to request a prescription through a medical questionnaire.

Once you have chosen your medicine and submitted the questionnaire, it will be assessed by one of our doctors. If suitable, the doctor will accept your request and a prescription will be issued. Your medicine will then be dispensed by our UK pharmacy and sent by tracked delivery to your address. Your medicine is usually dispatched within 24 hours after ordering.

Dosage instructions
Take ONE tablet weekly. Begin 10 days before departure (i.e. first intake 10 days before departure and 2nd intake 3 days before departure). Subsequent doses should be taken once a week (on a fixed day). Treatment should be continued for 4 weeks after leaving a malarious area (minimum treatment period 6 weeks).