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Diarrhoea

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Loperamide

Loperamide capsules are taken to relieve the symptoms of diarrhoea. This medication is able to reduce the frequency of bowel movements, allowing more solid and natural stools to form and allowing the body absorb more water and salts which are usually lost while experiencing diarrhoea. Loperamide may be taken to treat either short-term diarrhoea or diarrhoea associated with irritable bowel syndrome (IBS).

See Loperamide patient information leaflet

Last PIL review date: 16/09/2019

Prices start from £15.00 for 30 capsules

£ 15 InStock
Please note a final decision on a suitable medicine for your condition will be made by our prescriber once you have completed a consultation PLEASE CLICK HERE TO ANSWER SOME QUESTIONS ABOUT YOUR SYMPTOMS
Please note all the answers are reviewed by a doctor to assess eligibility
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  • Dronedarone
  • Velpatsavir
  • HIV treatments
  • Quinidine
  • Oral desmopressin
  • Antifungals similar to ketoconazole
  • Gemfibrozil
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Please use a minimum of 1 words.

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  • Severe diarrhoea associated with antibiotics
  • Inflammatory bowel disease such as Crohn's or colitis
  • Constipation, or your stomach appears to be swollen
  • Acute dysentery
  • Liver disease
  • Diarrhoea for more than 48 hours (unless associated with diagnosed IBS)
  • Intolerant to some sugars
  • Severe diarrhoea
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Please use a minimum of 1 words.

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  • You shouldn't take loperamide for regular diarrhoea for more than 48 hours. Speak to your GP if your symptoms are still present after this amount of time. 
  • If your diarrhoea is associated with IBS, you shouldn't take loperamide for more than 14 days without speaking to your doctor. 
  • Some people may feel tired after taking loperamide. If this happens to you, you should avoid driving or operating machinery until the feeling subsides
  • You should always drink plenty of fluids when you have diarrhoea, as you're more likely to become dehydrated. 
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  • You have an allergy or hypersensitivity to loperamide
  • You've used this treatment before and suffered from serious side effects
  • You're already taking loperamide for something other than diarrhoea
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Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Loperamide?

Loperamide is a medication used to treat acute diarrhoea. It can be used against both short-term diarrhoea symptoms and lengthier diarrhoea caused by irritable bowel syndrome (IBS). Available in the form of capsules that are swallowed, Loperamide is a generic version of the diarrhoea medication called Imodium.

How does Loperamide work?

This medication reduces the symptoms of diarrhoea by working on specific nerve receptors in the gut. The changes to these receptors mean they are less sensitive to the signals which cause muscle contractions in the intestine, causing food to pass through more slowly and reducing the frequency of bowel movements. This adjustment also allows water and salts that are usually lost in diarrhoea to be absorbed by the body, so patients should feel more hydrated and healthier while also able to produce firmer stools.

How is Loperamide taken?

Loperamide capsules can be taken by adults and adolescents aged 12 years old and over when treating short-term diarrhoea or just adults aged 18 and above when treating IBS diarrhoea. The exact instructions on dosage depends on which type of diarrhoea is being treated.

For dealing with short-term diarrhoea, it’s recommended you take two capsules to start treatment. Then one capsule is taken after each loose bowel movement. Do not take more than six capsules within a 24-hour period and do not take this medication for attack which last longer than 48 hours. If you experience a diarrhoea attack that lasts more than this time, then stop taking Loperamide and talk to your doctor for advice.

When treating IBS diarrhoea, the dosage to start treatment is again two capsules and then one capsule is taken after each loose bowel movement (or as advised by your doctor). This mediation can be used for treating this specific condition for up to two weeks, but you should contact your doctor if an attack lasts for over 48 hours. Again, avoid taking more than six capsules in a 24-hour period.

What are the side effects of Loperamide?

Like with all medicines, it is possible to experience side effects while taking Loperamide, but not everyone will get them and most of the ones possible are mild. The most common side effects that could occur with this medication are feelings of sickness, constipation or wind and headaches. Other potential side effects are much rarer but some can be serious so you should talk to your doctor or pharmacist as soon as possible if you experience them.

You should put a hold on using this medication and speak to your doctor right away if you experience any of these following side effects:

  • An allergic reaction which includes shortness of breath, unexplained wheezing, passing out or swelling of the face and throat
  • Uncoordinated movements, loss of consciousness or reduced level of consciousness
  • Skin rashes, which may include blistering or peeling skin
  • Itchiness or hives
  • Stomach pain or swollen stomach
  • Difficulties passing water
  • Severe constipation
  • Miosis (narrowing of the pupils of the eye)

Can I use Loperamide?

This medicine is suitable for most people to use as treatment for diarrhoea, but certain health conditions and other personal factors including medication you’re currently taking could prevent you from using Loperamide safely. For instance, you should avoid taking this treatment if you are aged under 12 or you have IBS diarrhoea and aged below 18. You should also check with your doctor before taking this medication if you are either pregnant, planning to get pregnant or breast-feeding. Small amount of this medication could get into breast milk.

It’s vital to avoid taking Loperamide if you have any of the following conditions:

  • A flare-up of an inflammatory bowel condition such as ulcerative colitis
  • Constipation (or your stomach appears swollen)
  • Acute dysentery (symptoms can include blood in your stools and high temperature)
  • Your severe diarrhoea began after taking antibiotics

Speak to your doctor or pharmacist if any of these apply to you. You should also speak to one of them before using this treatment if you have any of these conditions (which may not prevent you from using Loperamide but may require precautionary steps):

  • AIDS (you should stop taking Loperamide immediately if you have AIDS and your stomach becomes swollen while using this medication)
  • Liver disease
  • You have been told you have an intolerance to some sugars (this medication contains lactose)

You should also make your doctor or pharmacist aware of any other medications you are currently taking (or have recently taken) as some could disrupt the effects of Loperamide. You should especially highlight these medicines if you use them:

  • Ritonavir (for treating HIV)
  • Quinidine (treats abnormal heart rhythms or malaria)
  • Oral desmopressin (treats excessive urination)
  • Itraconazole or ketoconazole (treats fungal infections)
  • Gemfibrozil (treats high cholesterol)

What if I use too much Loperamide?

If you take more of this medication than you are meant to then you should immediately contact your doctor or visit your nearest hospital emergency department. Having too much of this treatment can cause a wide range of symptoms, some of which can potentially have life-threatening consequences). The symptoms can include:

  • Increased heart rate
  • Irregular heartbeat
  • Weak breathing
  • Muscle stiffness
  • Uncoordinated movements
  • Drowsiness
  • Difficulty urinating

Is Loperamide enough to cure my diarrhoea?

While Loperamide can make a big difference against the symptoms of diarrhoea, the condition can still make you lose large amounts of fluids and salts. These will need replacing by drinking more liquid than usual. For guidance, you could ask your pharmacist about rehydration therapy to replace lost salts. Replacing fluids and salts is especially important for children and any frail or older patients.

How is my order shipped to me?

When an order is ready for shipping, it is collected and delivered by either the Royal Mail or DPD depending on your preference (or possibly your location or the item you ordered). Each order is assigned a tracking number, which will be emailed to you at the time of dispatch. Your medicine will be sent in plain and discreet packaging that’s eco-friendly. We do not include any branding on our packaging nor any labels which inform readers what type of product is contained within.

Advice on Addiction and Medication Restrictions

If you are at all worried or concerned about an addiction to any type of medication, we urge you to speak to a professional for help and advice. Below are links to organisations that can help.

  • Talk To Frank

  • NHS Help & Advice On Drug Addiction
  • Dosage Instructions
    In one capsule is 2mg of loperamide hydrochloride. These are taken as directed by your prescriber for acute diarrhoea, and for no longer than one day.
    Active ingredient: Loperamide Hydrochloride
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    Loperamide Dosage Quantity Cost Including Consultation
    Loperamide 2mg 30 Capsules £15.00
    Loperamide 2mg 60 Capsules £30.00
    Loperamide 2mg 90 Capsules £45.00
    Loperamide 2mg 180 Capsules £90.00
    Loperamide 2mg 210 Capsules £105.00

    Delivery Charges

    The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

    UK Standard Delivery, £1.99

    Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

    standard UK delivery within 3-5 working days

    Additional terms and conditions apply.

    UK Express Delivery, £2.99

    Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

    If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

    Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, £14.99

    Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply

    DPD Saturday Delivery, by 12:00am, £21.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, by 10:30am, £29.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply, please see below.

    US and outside the UK

    Unfortunately, we can't process orders from outside the UK at this time.


    Terms and Conditions

    Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

    All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

    Active ingredient: Loperamide Hydrochloride
    In stock