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Malarone is a medication used to prevent and treat Malaria. The two active ingredients in the tablets are atovaquone and proguanil. 

See Malarone Anti-Malarial Tablets Patient Information Leaflet

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Malarone Anti-Malarial Tablets
  • Atovaquone or Proguanil Chloride (Malarone)
  • Doxycycline Mefloquine (Lariam)
  • Quinine or Quinidine Chloroquine
  • Any antibiotics

You can confirm this by checking the NHS fitfortravel website

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  • Medicines that are used to thin your blood, such as warfarin or other Vitamin K blockers. 
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  • You will read the Patient Information Leaflet supplied with your medication
  • You will contact us and inform your GP of your medication if you experience any side effects of treatment, if you start new medication, or if your medical conditions change during treatment
  • The treatment is solely for your own use
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  • You have answered all the above questions accurately and truthfully
  • You understand our doctors take your answers in good faith and base their prescribing decisions accordingly, and that incorrect information can be hazardous to your health
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Malarone is a medication used to prevent and treat Malaria. The two active ingredients in the tablets are atovaquone and proguanil. 

See Malarone Anti-Malarial Tablets Patient Information Leaflet


What is Malarone and what does it do?

Malarone is a medicine containing the two active ingredients atovaquone and proguanil. It is used to prevent and treat Malaria.

Malaria is a disease that spreads to humans via mosquitoes. The mosquitoes pass on the parasite by biting. When Malarone is taken to prevent Malaria, the active ingredients in the treatment kills off the parasites before they cause illness.

When is Malarone prescribed?

Malarone can be prescribed to prevent Malaria. It is primarily prescribed to patients travelling to Malaria risk areas. These areas include, but are not limited to large areas of Africa and Asia, Central and South America and parts of the Middle East.

No antimalarial treatment gives complete protection against Malaria, so it is important that you also take other preventative measures to decrease the risk as much as possible. Always use mosquito repellent and clothing to protect yourself and if possible a mosquito net at night.

To find our whether the country you are visiting belongs to any of the Malaria risk areas, visit the NHS Fit for Travel website.

Is Malarone suitable for my condition?

Our doctors will use the information you provide us through the medical questionnaire to determine whether this medicine is suitable for you to take. Malarone may not be suitable or prescribed if any of the following applies to you:

  • If you are allergic or sensitive to atovaquone, proguanil or any of the ingredients listed in the patient information leaflet.
  • If you have severe kidney disease.

Some medicines can affect how Malarone works. Always list any other medication you may take in the medical questionnaire. This will help our doctors determine the suitability of this medicine, and reduce the risk of side effects.

Medicines that can interact with Malarone include, but are not limited to metoclopramide, antibiotics (tetracycline, rifampicin and rifabutin), efavirenz, warfarin and etoposide.

What is the recommended dosage of Malarone?

You should follow the doctor’s instructions on how to take this medicine. The doses outlined below is for your reference only. The tablet should be taken with food or a milky drink where possible. Take the tablet at the same time every day.

Never exceed the stated dose.

Malarone doses for adults

The recommended dose for adults is 1 tablet once a day.

Start taking Malarone 1 to 2 days before travelling. Malarone needs to be taken throughout your stay. After your return to a malaria free area, keep taking Malarone for another 7 days before stopping.

Does Malarone cause any side effects?

Yes, just like all medicines Malarone may cause side effects. However, not everyone will get them. It is important that you read through the patient information leaflet before use so that you know how to recognise side effects and when to seek medical advice.

Common side effects from taking Malarone include (but are not limited to):

  • Headache.
  • Feeling or being sick (nausea and/or vomiting).
  • Stomach pain.
  • Diarrhoea.
  • Sleeping problems.
  • Loss of appetite.

Contact your GP or surgery immediately if you notice any signs of a severe allergic reaction.

Can I reduce the risk of getting side effects?

Yes. You should always read the patient information leaflet thoroughly before use as this can help reduce the risk of side effects and interactions between medicines. Below are a few things you can do:

  • While filling in the medical questionnaire, remember to include any other medicines you are taking. Malarone can affect how other medicines work, so it is important that you tell our doctors about all medicine you take. Don’t forget to also include over the counter medication and supplements.
  • Take Malarone with food or a milky drink to help your body absorb as much as possible of the medicine.
  • Take Malarone at the same time every day.

How do I buy Malarone online?

To legally and safely buy Malarone online you need a prescription from a GMC (General Medical Council) registered doctor. Our online doctor service allows you to request a prescription through a medical questionnaire.

Once you have chosen your medicine and submitted the questionnaire, it will be reviewed by one of our doctors. If suitable, the doctor will accept your request and a prescription will be issued. Your medicine will then be dispensed by our UK pharmacy and sent by tracked delivery to your chosen address. Your medicine is usually dispatched within 24 hours after ordering.

Dosage instructions
Take ONE tablet daily, start taking 1-2 days before entering endemic area, during your stay, and continue to take for 7 days after leaving.