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HRT (Menopause)

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Novofem

Novofem tablets are used for sequential combined hormone replacement therapy (HRT). There are two types of tablets found in a pack of this treatment, and they add two particular hormones into the body (oestrogen and progesterone). The treatment minimises the symptoms which women can experience during the menopause.

This treatment can also help women experiencing the menopause who are more at risk of fractures due to osteoporosis, if other medications are not deemed suitable.

Prices start from £42.00 for 84 tablets

£ 42 InStock
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  • Jaundice (usually characterised by your skin or the whites of the eyes turning yellow)
  • Significantly increased blood pressure (you may notice headaches, dizziness, and feeling more tired)
  • New onset of migraine, which may be with or without aura
  • Chest pain that radiates to the arm and/or neck
  • Signs of a blood clot
  • Any breast changes such as dimpling, puckering, nipple discharge, or any other abnormality
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  • Epilepsy medications
  • Medicines for tuberculosis
  • HIV treatments
  • St John's Wort
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You have an allergy to norethisterone or estradiol You've used this treatment in the past and suffered with serious side effects You're already using a treatment that contains norethisterone or estradiol for any reason other than hormone replacement therapy
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What is Novofem

Novofem is a tablet used for Hormone Replacement Therapy (HRT) which treats women experiencing symptoms of the menopause. It is used by postmenopausal women when it has been at least six months since their last natural period.

Novofem is considered a sequential combined form of hormone replacement therapy and contains two types of tablets. One type exclusively contains the hormone oestrogen (estradiol) and the other type adds a different hormone called progesterone.

How does Novofem work?

The two hormones added to the body by Novofem have separate but equally important jobs. When a woman is going through the menopause the amount of oestrogen their body naturally produces drops significantly, and it’s this change that causes many of the symptoms that can flare up during this phase.

The oestrogen added by these tablets makes up for this natural reduction in the body. The progesterone, meanwhile, performs a balancing function to make sure that oestrogen levels do not rise to a point where they may become potentially hazardous.

Novofem can also be used to prevent osteoporosis after the menopause. Women who are more susceptible to the bone-weakening condition face an increased risk of fractures during and after the menopause. But various HRT tablets including Novofem can serve as treatment for this particular concern.

How do I take Novofem?

A single month’s supply of Novofem comprises of 16 red tablets which contain oestrogen and 12 white tablets which contain oestrogen and progesterone. A tablet is taken once a day and at about the same time each day with a glass of water. You can take this medication either with or without food.

When completing a month’s supply, the red tablets are taken between the 1st and 16th day of the course and the white tablets are taken between the 17th and 28th day. When one month’s supply is completed, you’ll move on to the next without interruption.

What are the side effects of Novofem?

There are numerous side effects that can be experienced when taking this medication, although not all users will experience any. The most common side effects associated with Novofem include the following:

  • Headaches
  • Breast tenderness
  • Increased blood pressure
  • Vaginal infection with a fungus (e.g. thrush)
  • Dizziness and sleeplessness
  • Dyspepsia (indigestion), abdominal pain and flatulence
  • Nausea
  • Rash and itching
  • Vaginal bleeding
  • Swelling of hands, ankles and feet (oedema)
  • Weight increase
  • Aggravation of uterine fibroids (benign tumour of the womb)

Other side effects are possible but far less likely to occur. However, certain diseases have been reported more often in women who use HRT when compared to women who do not use HRT. These conditions include the following:

  • Breast cancer
  • Abnormal growth or cancer found in the lining of the womb
  • Heart disease
  • Blood clots in the veins of the legs or lungs
  • Ovarian cancer
  • Stroke
  • Memory loss if HRT is started over the age of 65

Can I take Novofem?

Novofem is meant to be taken by women who are experiencing symptoms of menopause and have not had any periodic bleeding for at least six months. If you are not switching from another HRT, then you can start treatment immediately. If you are switching HRT however, then you should ask your doctor when it’s the right time to start using the medication.

You should avoid taking Novofem tablets if you have or have ever had any of the following health conditions:

  • Breast cancer
  • Any form of cancer that is sensitive to oestrogens (e.g. cancer of the womb lining)
  • Unexplained vaginal bleeding
  • Excessive thickening of the womb lining
  • Blood clot in a vein within the legs or lungs
  • A current or recent disease caused by a blood clot (e.g. heart attack, stroke or angina)
  • A rare blood problem named porphyria

Certain medicines may interfere with the effect of Novofem, which could cause irregular bleeding. This applies to the following:

  • Medicines for epilepsy (including phenobarbital, phenytoin and carbamazepine)
  • Medicines for tuberculosis (including rifampicin and rifabutin)
  • Medicines for HIV infection (including nevirapine, efavirenz, ritonavir and nelfinavir)
  • Medicines for hepatitis C infections (including telaprevir)
  • Herbal remedies that contain St John’s Wort (Hypericum perforatum)

Furthermore, medicines containing ketoconazole (a fungicide) can possibly increase the effects of Novofem.

This medication is not designed for women experiencing a premature menopause (due to surgery or ovarian failure). If you have a premature menopause, then the risks of using HRT could be different compared to normal circumstances. It’s best to talk to your doctor about the best course of action.

What if I take too much or too little Novofem?

If you end up taking more of this treatment then you are meant to, talk to a doctor or pharmacist as soon as you can. An overdose of the hormones contained in this medicine can lead to numerous symptoms including breast tenderness, nausea, vomiting, vaginal bleeding, depressive mood, fatigue, acne and growth of body or facial hair (hirsutism).

Forgetting a dose of Novofem is not a big problem but does increase the likelihood of breakthrough bleeding or spotting. If you forget to take a tablet and it’s less than 12 hours after you were meant to have it, take the tablet as soon as you remember. If it has been more than 12 hours since you were meant to take the tablet, just start again as normal on the next day. Don’t take a double dose to compensate for a forgotten tablet.

How is my order shipped to me?

When an order is ready for shipping, it is collected and delivered by either the Royal Mail or DPD depending on your preference (or possibly your location or the item you ordered). Each order is assigned a tracking number, which will be emailed to you at the time of dispatch. Your medicine will be sent in plain and discreet packaging that’s eco-friendly. We do not include any branding on our packaging nor any labels which inform readers what type of product is contained within.

Advice on Addiction and Medication Restrictions

If you are at all worried or concerned about an addiction to any type of medication, we urge you to speak to a professional for help and advice. Below are links to organisations that can help.

  • Talk To Frank

  • NHS Help & Advice On Drug Addiction
  • Dosage Instructions
    1 red tablet daily for 16 days, then 1 white tablet daily for 12 days, subsequent courses are repeated without interval; start treatment with red tablet at any time or if changing from cyclical HRT, start treatment the day after finishing oestrogen plus progestogen phase.
    Active ingredients: Estradiol Hemihydrate, Norethisterone Acetate
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    Novofem Dosage Quantity Cost Including Consultation
    Novofem 1mg/1mg 84 Tablets £42.00

    Delivery Charges

    The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

    UK Standard Delivery, £1.99

    Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

    standard UK delivery within 3-5 working days

    Additional terms and conditions apply.

    UK Express Delivery, £2.99

    Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

    If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

    Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

    Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

    Additional terms and conditions apply.

    DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, £14.99

    Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply

    DPD Saturday Delivery, by 12:00am, £21.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply.

    DPD Saturday Delivery, by 10:30am, £29.99

    Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

    If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

    Additional terms and conditions apply, please see below.

    US and outside the UK

    Unfortunately, we can't process orders from outside the UK at this time.


    Terms and Conditions

    Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

    All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

    Active ingredients: Estradiol Hemihydrate, Norethisterone Acetate
    In stock