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Paludrine Anti-Malarial Tablets

Paludrine tablets belong to a group of medicines known as ‘anti-malarials’. They are taken by adults and children who are planning to visit a place where malaria is known to be present and it provides protection from this disease. When prescribed paludrine, these tablets are taken on a daily basis for a week before visiting an area where malaria is present and the medicine is taken during and after the visit too. Anti-malarials like paludrine are popularly used by people who travel to certain countries and they provide very effective protection against the symptoms of malaria, which is a disease spread by mosquitoes.

Last Patient Information Leaflet Review Date: 14/04/2020

See Paludrine Patient Information Leaflet

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Please note a final decision on a suitable medicine for your condition will be made by our prescriber once you have completed a consultation PLEASE CLICK HERE TO ANSWER SOME QUESTIONS ABOUT YOUR SYMPTOMS
Please note all the answers are reviewed by a doctor to assess eligibility
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  • Anticoagulants
  • Antacids
  • HIV treatments
  • Pyrimethamine
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Please use a minimum of 1 words.

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  • You should start taking proguanil a week before you arrive in the malaria zone. You should then take it every day throughout your stay, and for 4 weeks after you return to a malaria-free area.
  • If you have an allergic raection to proguanil, you must stop taking it and see a doctor immediately
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Please use a minimum of 1 words.

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  • You have an allergy or hypersensitivity to proguanil hydrochoride
  • You've used this treatment before and suffered from serious side effects
  • You're already taking proguanil hydrochloride for something other than prevention of malaria
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Dr Daniel Cichi has 20 years experience as a doctor and now he is a senior GP. He worked in A&E departments, GP surgeries and on cruise ships.

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Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

Paludrine tablet

Paludrine is the name of an anti-malarial medicine. ‘Anti-malarials’ such as this one can be used in certain parts of the world to help protect yourself from getting the infectious disease known as malaria. The disease is spread by infectious mosquitoes and anti-malarials are often used by people who travel to countries where there is a high concentration of mosquitoes and the risk of malaria is present. An anti-malarial medicine such as paludrine may be prescribed to a person if they will soon be travelling to a country where malaria occurs, or they live in an area where malaria is present and they are not immune to it.

If you are going to be somewhere where malaria is present, then you should consult a doctor in advance to confirm if you should be prescribed an anti-malarial and which one to use. Paludrine comes as tablets and is one of the options you may be given if it’s considered appropriate for you to be given anti-malarials. You may need to take another medicine alongside paludrine for maximum protection and it is always recommended you take precautions to reduce your risk of getting mosquito bites. Paludrine can be taken by both adults and children.

How does Paludrine work?

Paludrine contains a medicine called proguanil hydrochloride. This treatment may be taken alongside chloroquine or atovaquone, which are other types of medicine designed to treat malaria. Paludrine is commonly used for parts of the world where a chloroquine-resistant strain of malaria has been reported.

Medicines like paludrine are able to prevent malaria symptoms from kicking in by restricting the activity of the parasite responsible for the illness. Different malaria treatments work in different ways, but what they all have in common is that they attack the parasite which causes malaria, denying it the capacity to grow and making it vulnerable to the body’s natural defences.

Can I use Paludrine?

You need a prescription from a qualified doctor before you can purchase an anti-malarial medication such as paludrine. If you are considering acquiring and taking paludrine (or giving it to your child), then it is important to have a consultation with a doctor to determine that such medication is safe and appropriate to be used.

Certain circumstances may mean you need to take precautions with this medicine (such as a lower dose) or avoid using paludrine completely. For instance, you should tell your doctor before using this medicine if you have ever had problems with your kidneys.

You should also inform your doctor or local pharmacist about any other medicines you are currently using, to check that there aren’t any that could clash with the effects of paludrine. It’s particularly important to mention it if you are using warfarin or another medicine taken to prevent blood clots. Any antacids (which treat heartburn or indigestion) or boosted protease-inhibitors (which treat viral infections such as HIV/AIDS) you are taking should also be mentioned before using anti-malarials. You should also mention if you are going to have a live oral typhoid vaccination, since this also may make an adjustment of your paludrine dose necessary.

You also need to mention it if you are pregnant or breast-feeding. Pregnant women who require an anti-malarial medication tend to combine this with a supplement which contains folic acid. If you are travelling to an area where there is malaria with your baby, then the baby will require anti-malarial medicine too.

Something else to keep in mind as well is that if you live in a country where malaria occurs, then it’s possible you may be already slightly immune to the disease. That is just one of the reasons why consulting a doctor before using paludrine or similar products is so important.

Paludrine dosage instructions

When someone is prescribed paludrine tablets, they should start taking them one week before entering the malaria area they are going to (this applies regardless of the patient’s age). If it is not possible to start taking this medicine a week in advance, then you should start taking them at least two days before entering the malaria area. Patients should continue to take paludrine each day during their stay in the malaria area and they should keep taking the tablets for 4 weeks after leaving the malaria area.

The exact daily dosage recommended for you to take will depend on your age. If your doctor or pharmacist gives you specific instructions, then you/your child should follow these. Otherwise, you can follow the following instructions which are typical for particular age groups:

  • Aged 14 or above – Take two paludrine tablets daily
  • Aged 9 to 14 – Take one and a half tablets daily
  • Aged 5 to 8 – Take one tablet daily
  • Aged 1 to 4 – Take half a tablet daily
  • Under 1-year-old – Take a quarter of a tablet daily

Paludrine tablets are ideally taken at the same time each day and after eating food. The tablets or part tablets should be swallowed with a drink of water. However, young children can be given the tablets crushed in milk, honey or jam.

If you forget to take a dose of this medicine, then take it as soon as you remember, unless your next dose is almost due, in which case simply skip the forgotten dose. If you take more tablets then you should in a single day, then contact your doctor or go to a hospital right away for help and advice.

Paludrine side effects

Like with other medicines, paludrine could potentially cause side effects, but not everyone experiences them. The following side effects have been reported in some cases of people using paludrine:

  • Upset stomach
  • Diarrhoea
  • Constipation
  • Mouth ulcers
  • Inflamed mouth
  • Skin reactions
  • Hair loss
  • Inflammation of blood vessels
  • High temperature

While this list may look concerning, none of these possible side effects are particularly common so the chances are you won’t notice any and they will likely be short-lasting even if you do. If, however, you experience any symptoms which last for a long time or you experience an allergic reaction to this medication, then stop using paludrine and contact a doctor or hospital as soon as possible.

How is my order shipped to me?

When an order is ready for shipping, it is collected and delivered by either the Royal Mail or DPD depending on your preference (or possibly your location or the item you ordered). Each order is assigned a tracking number, which will be emailed to you at the time of dispatch. Your medicine will be sent in plain and discreet packaging. We do not include any branding on our packaging nor any labels which inform readers what type of product is contained within.

Dosage Instructions
Adults should take TWO tablets daily, starting from a week before visiting an area with malaria. Continue taking the tablets during every day in the area and for 4 weeks after leaving it.
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Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

Additional terms and conditions apply.

UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply

DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply, please see below.

US and outside the UK

Unfortunately, we can't process orders from outside the UK at this time.


Terms and Conditions

Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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