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Psoriasis

Silkis

Silkis is a medication that’s prescribed to patients with mild to moderate psoriasis. It contains calcitriol, a derivative of Vitamin D that helps to normalise skin cell production and growth.


Psoriasis is caused by the overproduction of skin cells, causing scaly plaques on the skin. Silkis reduces the appearance of these and prevents the skin from growing too quickly. Most people see results within 2 weeks.


Silkis is a topical treatment that should be applied directly to the affected area. A full, detailed description of how to use it can be found in the patient information leaflet (PIL).



Please see Silkis Patient Information Leaflet

Last Patient Information Leaflet Review: 15/01/2020


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Dr. Diana Gall GMC No. 7685129

Dr Diana Gall graduated from medical school in 2005 and has since undertaken further intensive training in many different areas of medicine. Dr Diana has reached consultant level and has practiced medicine all over Europe.

Shamir Patel GPHC No. 2049338

Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Silkis?

Silkis is a topical treatment for psoriasis. It comes in the form of an ointment that should be applied directly to the affected areas of skin.

Silkis can be used on up to a third of the body, but psoriasis that affects any more than this should be examined by your own doctor.

The ointment contains calcitriol, a derivative of vitamin D. It works on the affected skin by normalising skin cell growth, meaning that the lesions should reduce, as there shouldn’t be any excess production of skin.

Can I use Silkis?

Silkis is a fairly safe treatment for psoriasis, but there are some other conditions that might mean that the ointment isn’t the most suitable choice for you. These include:

  • Being treated with oral medicine for calcium deficiency
  • Kidney disease
  • Liver disease
  • High blood calcium levels
  • Abnormal calcium metabolism
  • Allergy to calcitriol or any other ingredients in Silkis

If you’ve been diagnosed with any of the above, you should visit your doctor to ask about whether Silkis is the right treatment for you or whether you should look at other options. If you don’t have any of the conditions listed, it should be safe for you to use Silkis for psoriasis plaques and lesions.

Will Silkis interact with any other medicines?

Despite being vitamin-derived, there are still some treatments that should be avoided if you plan to use Silkis. Alternatively, you should look at other medicines for psoriasis if you’re taking any of the medications listed here:

  • Thiazide diuretics
  • Digoxin
  • Drugs affected by changing calcium levels
  • Calcium supplements
  • Higher doses of vitamin D (i.e Fultium D3)
  • Peeling agents
  • Astringent agents
  • Irritant agents

The final three interactions listed here may cause the condition to worsen if used alongside Silkis. If you aren’t sure if you’re using any of these, you should make a list of anything that you put on your skin, including face-masks and non-medicated creams such as moisturisers, and take it into your local pharmacy. They should be able to look at the ingredients and tell you if the product is safe to use alongside Silkis or whether it should be avoided.

You should also write down any and all medicines you’re taking so that your GP or pharmacist can double-check whether it’s safe for you to use them in conjunction.

What are the side effects of using Silkis?

Silkis is designed to slow the production of skin cells down, so it’s natural that it can cause some side effects. Some people aren’t affected at all, others may feel some mild discomfort, and others might even stop using the treatment due to the severity of the side effects. Unfortunately, there’s no way of telling how it might affect you until you start using the ointment, but some of the most common side effects reported by users are:

  • Pruritus (skin itching)
  • Skin discomfort
  • Skin irritation
  • Skin redness
  • Dry skin
  • Worsening of psoriasis
  • Skin oedema
  • Contact dermatitis

If you experience any of the above, you should inform your doctor, even if they’re mild. Your GP might offer alternative treatments, and it’s completely your decision to try them if the side effects are bothering you.

Silkis might also cause an allergic reaction, which can be either local (around the site of application) or more severe. If you experience skin irritation, inflamed skin and redness, you should stop using Silkis and see your doctor for an allergy test. Don’t use the product again unless your doctor tells you it’s safe to do so. However, if you experience wheezing, shortness of breath, and swelling from the neck upwards, you should dial 999 and state that you may be experiencing anaphylaxis.

How do you use Silkis?

Silkis is fairly straightforward to use; it’s applied directly to the affected lesions. Make sure that you thoroughly wash and dry your hands as well as the areas you’re going to apply the ointment to. Apply a thin layer to the plaques and wash your hands straight away. Try to avoid healthy skin coming into contact with the ointment.

You shouldn’t use more than 30g of the treatment per day. It should be used in the morning and in the evening. If you do experience skin irritation, your doctor might want to reduce this to once a day.

Make sure you don’t cover any of the treated lesions with bandages or plasters as this might make more of the product be absorbed. This increases the risk or severity of side effects.

How long does Silkis take to work?

The time that it takes to start working can vary from person to person depending on their personal tolerance to the ointment and the severity of their condition. Most people will start to see a marked improvement within 2 weeks, so if you haven’t noticed a reduction in appearance or symptoms, you should visit your doctor to see if you’re responding well to Silkis.

If your condition worsens in this time, you should stop using Silkis and go back to your doctor.

The duration of your treatment will depend on your doctor’s advice.

Can I use Silkis for acne?

Silkis is only indicated for use in patients with psoriasis. You shouldn’t use Silkis for acne or any other skin condition. You must have diagnosed psoriasis to use the ointment. Applying it to any other skin condition might make it worse.

Dosage Instructions
Apply a thin layer of ointment over the affected area TWICE a day, morning and evening.
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Silkis Dosage Quantity Cost Including Consultation
Silkis 3mcg £45.99

Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

Additional terms and conditions apply.

UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply

DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply, please see below.

US and outside the UK

Unfortunately, we can't process orders from outside the UK at this time.


Terms and Conditions

Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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