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Spedra is a medicine used in adult men to help aid an erection. Spedra tablets are taken 15 - 30 minutes before sexual activity and are available in doses of 50mg, 100mg and 200mg. The active ingredient in Spedra is Avanafil

See Spedra (Avanafil) Tablets Patient Information Leaflet

Last PIL Review Date: 11/03/2019

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Spedra (Avanafil) Tablets
14 units of alcohol equal: 14 single measures of spirits (ABV 37.5%); seven pints of average-strength (4%) lager; nine and one-third 125ml glasses of average-strength (12%) wine. Please be advised that the recommended units per week is less than 14 units spread out over more than 3 days.

This means any of the following:

  • Low blood pressure requiring investigation
  • Low blood pressure requiring treatment
  • Being prone to faint or feel light-headed for more than a few seconds when standing up quickly or standing for long periods
  • Heart problems (including angina, chest pain, heart failure, irregular heart beats, heart attack, left-ventricular outflow obstruction, cardiomyopathy or valvular heart disease)
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  • An erection that lasted more than 4 hours
  • Any physical condition affecting the shape of the penis (e.g. angulation, Peyronie's disease and cavernosal fibrosis)
  • Inherited eye disease - retinitis pigmentosa
  • Galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption
  • Any serious medical condition which may require immediate hospitalisation
  • Any treatment for erectile dysfunction apart from Viagra (Sildenafil), Levitra (Vardenafil), Cialis (Tadalafil), or Spedra (Avanafil)
  • Medicinal nitrates, such as Glyceryl trinitrate, Isosorbide mononitrate or isosorbide dinitrate (including oral, transdermal and sublingual)
  • Recreational drugs prohibited by law (Class A, B or C) - Recreational nitrates such as amylnitrate (also known as 'poppers'), Alpha blockers (used to treat high blood pressure or urinary symptoms associated with benign prostatic hyperplasia, and including Doxazocin, Prazocin, Terazocin and Indoramin)
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  • Phenobarbital, Phenytoin, Carbamazepine (anticonvulsant medicines)
  • Please ensure a gap of 24 hours (26 hours Cialis)  between usage.
  • Please never exceed the prescribed dose. 
  • You will read the Patient Information Leaflet supplied with your medication
  • You will contact us and inform your GP of your medication if you experience any side effects of treatment, if you start new medication, or if your medical conditions change during treatment
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Spedra is a medicine used in adult men to help aid an erection. Spedra tablets are taken 15 - 30 minutes before sexual activity and are available in doses of 50mg, 100mg and 200mg. The active ingredient in Spedra is Avanafil

See Spedra (Avanafil) Tablets Patient Information Leaflet

Last PIL Review Date: 11/03/2019


What is Spedra and what does it do?

Spedra is a medicine used in adult men to help aid an erection. Spedra tablets are taken 15 - 30 minutes before sexual activity and is available in doses of 50mg, 100mg and 200mg.

Spedra contains the active ingredient avanafil, and works by increasing blood flow to the penis. Please note, this treatment does not cause an erection, but aids erection in combination with sexual stimulation.

When is Spedra prescribed?

Spedra tablets may be prescribed to adult men suffering from erectile dysfunction. Erectile dysfunction, commonly referred to as impotence, is a common condition which affects up to half of all men aged 40 to 70 at some point in their lives.

Before requesting a prescription for Spedra, we recommend that you consider lifestyle changes in order to reduce your symptoms. Losing weight if you are overweight and quitting smoking may help you regain an erection without prescribed medicines.

Is Spedra suitable for my condition?

The suitability of this treatment will be assessed by our doctors when you request your prescription. Spedra is likely to be suitable as long as the below does not apply to you. Do not take Spedra tablets if you:

  • Are allergic or sensitive to avanafil or any other ingredients listed in the patient information leaflet.
  • Are taking nitrate medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate.
  • Are taking medicines for HIV or AIDS, such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir.
  • Are taking any medicines for fungal infections, such as ketoconazole or saquinavir.
  • Have severe heart problems or have previously had a heart attack or stroke.
  • Have serious liver or kidney problems.
  • Are taking riociguat to treat high blood pressure in the lungs (pulmonary arterial hypertension).

Please note, the above is not a complete list. Always consult your own GP before ordering this medicine if you have any questions or are unsure of the suitability of this treatment.

What is the recommended dosage of Spedra?

You should follow the doctor’s instructions on how to take this medicine. The doses outlined below is for your reference only.

Spedra doses for men

The recommended starting dose is 100mg taken 15 - 30 minutes before sexual activity. Swallow the tablet whole with a glass of water. The tablet can be taken with or without food, but the effect may be delayed if taken with a large meal.

Does Spedra cause any side effects?

Yes, Spedra may cause side effects, just like all medicines. However, not everyone will experience them as the susceptibility to side effects varies from person to person.

Common side effects associated with taking Spedra includes, but are not limited to:

  • Headache.
  • Flushing.
  • Nasal congestion.

Consult you GP or nearest clinic immediately if you notice any signs of serious side effects, such as an erection that will not go away, blurred or sudden loss of vision or sudden decrease or loss of hearing.

Can I reduce the risk of getting side effects?

Yes, the risk of side effects can be reduced by letting our doctors know about any other medicines you take. Also let them know about any medical condition you may have. You can pass this information on by including it in the medical questionnaire when you request your prescription.

How do I buy Spedra online?

To legally and safely buy Spedra tablets online you need a prescription from a GMC (General Medical Council) registered doctor. Our service offers you the convenience to order your medicine from the comfort of your own home by filling in an online medical questionnaire.

Once you have chosen your medicine and submitted the questionnaire, it will be assessed by one of our GMC registered doctors. If suitable, the doctor will accept your request and a private prescription will be issued. Your medicine will then be dispensed by our UK pharmacy and sent by tracked delivery to your address. Your medicine is usually dispatched within 24 hours after ordering.

Dosage instructions
Take ONE tablet daily approximately 30 mins before sexual activity. Adjust according to response. Maximum of 200mg daily as a single dose. Please read leaflet.