What is Tadalafil?
Tadalafil is a drug that’s used for the treatment of erectile dysfunction in men. It’s part of the PDE-5 inhibitor family of medicines which also includes sildenafil, vardenafil and avanafil. Tadalafil is the generic version of the branded medication, Cialis.
Tadalafil works in a similar way to all of the other PDE-5 inhibitor drugs when used for the treatment of erectile dysfunction.
How does Tadalafil work?
Tadalafil helps to increase the blood flow to the penis, encouraging an erection. Erectile dysfunction is classified by the inability to achieve or maintain an erection hard enough or for a long enough time to have sex.
Tadalafil (and other PDE-5 inhibitors) helps to relax the blood vessels and soft muscle in your penis, encouraging blood flow to the area. However, it doesn’t just cause an erection once you’ve taken it. For tadalafil to work and for you to achieve an erection, you still need to be sexually aroused or stimulated. If you don’t have the desire to have sex, the medication isn’t likely to work for you and you should speak to your GP about other treatments that could be available for that issue.
Can I take Tadalafil?
If you’re a man and struggling with erectile dysfunction, there are some things you should know before starting treatment with tadalafil. Whilst it’s safe for most to take, it can cause some adverse and even dangerous effects in some. There are some groups of men that should take caution when using the medication, and if you’ve been diagnosed with any of the following conditions or medical problems, you should speak to your own doctor before ordering this medication, as it might not be suitable for you.
- Allergic to tadalafil or any of its ingredients
- If you’re taking any form of nitrates (usually used for heart problems) including the recreational drug, “poppers”
- Serious heart disease
- Recent heart attack (in the last 3 months)
- Recent stroke (in the last 6 months)
- Uncontrolled hypertension
- Stroke of the eye
- Hereditary eye disease
- Sickle cell anaemia
- Multiple myeloma
- Severe kidney problem
- If you’ve had pelvic surgery
- If you’ve had part or all of your prostate gland removed
If any of these conditions apply to you, you might want to discuss alternative treatment options with your pharmacist or doctor. There are also some medicines which might make it dangerous for you to take tadalafil, so if you’re on any of the following drugs, please consult your doctor before taking this medicine.
- 5-alpha reductase inhibitors
- Alpha blockers
- High blood pressure medicines
- Other medicines for erectile dysfunction
- Protease inhibitors (for HIV)
You should also avoid eating grapefruit or drinking grapefruit juice as this may affect how tadalafil is absorbed by your body.
What are the side effects of tadalafil?
As any medicine can, tadalafil carries the risk of causing side effects. Some men don’t experience them at all, whilst others experience them mildly or to quite a severe degree. It’s up to you whether the overall benefits of tadalafil outweigh the symptoms associated with taking it. Some of the most common complaints and symptoms from men using the medicine include:
- Back pain
- Muscle pains
- Pain in arms and legs
- Facial flushing
- Nasal congestion
- Difficulty breathing
- Prolonged erection (more than 4 hours)
- Nose bleeds
- Swelling of the hands and feet
- Stomach ache
- Blurred vision
- Eye pain
- Blood in urine
- Pounding heart sensation
- High or low blood pressure
There are some side effects that are more serious than others, and if you experience them, you should seek emergency medical help. These include:
- Allergic reaction
- Chest pain (do not take nitrates for this)
- Prolonged or painful erection (lasting more than 4 hours)
- Sudden loss of vision
There are more side effects listed in the patient information leaflet (PIL). We’ve only listed the most common complaints on this page. You can find the PIL in your medication box, or at the top of this page under the description of the medication. It’s important to read it thoroughly to understand exactly how to take it and what risks it may bring.
How do you take Tadalafil?
Unlike other PDE-5 inhibitors, there’s more than one way to take tadalafil. You can use it as any other medicine in the same family, and take a tablet 30-60 minutes before you plan to have sex, or you can take a lower dose once a day.
Many men prefer to use tadalafil in this way because it allows for spontaneity in sex, rather than having to plan for it or wait for an erection to develop. If you use tadalafil daily, it should take around 5 days to build up in your system, but it should work every time you’re sexually aroused.
Tadalafil comes in the following doses:
If you’re taking the medication daily, you’ll start off with 2.5mg, which may be increased to 5mg if this doesn’t have the desired effect. If you’re using it on-demand, you’ll likely be started on 10mg which you can then increase to 20mg if you find the lower dose isn’t strong enough.
What’s the difference between tadalafil and other PDE-5 inhibitors?
As we’ve already seen, tadalafil can be taken daily (meaning you don’t need to plan for sex or wait for the drug to kick in). The other difference between tadalafil and other PDE-5 inhibitors is the fact that it lasts much longer. Sildenafil (Viagra) tends to stay in your system for around 4-6 hours after taking it, where tadalafil lasts for around 36 hours. This doesn’t mean that your erection will last this long, but it does mean that the potential for developing one will last longer than with other, similar medicines.
Will tadalafil affect my fertility?
There were some studies that showed a slight decrease in sperm count in dogs and some men after taking tadalafil, but there’s no evidence to suggest that it will affect your fertility. However, if you have concerns about this, please talk to your doctor.
How is my order shipped to me?
When an order is ready for shipping, it is collected and delivered by either the Royal Mail or DPD depending on your preference (or possibly your location or the item you ordered). Each order is assigned a tracking number, which will be emailed to you at the time of dispatch. Your medicine will be sent in plain and discreet packaging that’s eco-friendly. We do not include any branding on our packaging nor any labels which inform readers what type of product is contained within.