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Vokanamet

Vokanamet is a medicine that’s used to treat type 2 diabetes. It contains canagliflozin and metformin, two drugs that work together in different ways to lower and control blood glucose levels. People with type 2 diabetes often experience high blood sugar levels, which can be dangerous and cause several serious health problems, but Vokanamet is an effective treatment that can control the condition.


It can be used either on its own, or with other medications If Vokanamet alone isn’t enough to bring down the blood glucose levels to a sufficient degree. This is a discussion that you need to have with your doctor.


Vokanamet is usually prescribed if diet and exercise alone haven’t been effective at controlling the condition.



Vokanamet Patient Information Leaflet

Last Patient Information Leaflet Review: 20/01/2020



£ 53.99 InStock
Please note a final decision on a suitable medicine for your condition will be made by our prescriber once you have completed a consultation PLEASE CLICK HERE TO ANSWER SOME QUESTIONS ABOUT YOUR SYMPTOMS
Please note all the answers are reviewed by a doctor to assess eligibility
1
2

Please use a minimum of 1 words.

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  • Allergy to canaglfilozin or metformin
  • Liver problems
  • Severely reduced kidney function
  • Uncontrolled diabetes with hyperglycaemia, nausea, vomiting, diarrhoea, rapid weight loss, lactic acidosis or ketoacidosis
  • Severe infection
  • Dehydration
  • Diabetic pre-coma
  • Recent heart attack
  • Heart failure
  • Serious problems with your ciruculation
  • Breathing difficulties
  • Drink excessive amounts of alcohol
4
  • Other treatments for diabetes (unless they've also been prescribed by your own GP to use in conjunction with canagliflozin and metformin)
  • Diuretics
  • St John's Wort
  • Carbamazepine
  • Phenobarbital
  • Phenytoin
  • Efavirenz
  • Ritonavir
  • Rifampicin
  • Chloestyramine
  • Digoxin
  • Digitoxin
  • Dabigatran
  • Cimetidine
  • Medicines that contain alcohol
  • Corticosteroids
  • Beta-2 agonists such as bronchodilators used for asthma
  • NSAIDs
  • COX-2 inhibitors
  • ACE inhibitors
  • Angiotensin II receptor antagonists
5

Please use a minimum of 1 words.

6
7
  • You have an allergy to canagliflozin or metformin
  • You've taken this treatment in the past and suffered from serious side effects
  • You're already taking canagliflozin or metformin in another medicinal form, or using either medication to treat another condition
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What is Vokanamet?

Vokanamet is a brand of medicine that’s prescribed to control blood glucose levels in patients with type 2 diabetes. It contains the medicines canagliflozin and metformin, which work in different ways to control blood sugar levels. Vokanamet can also help to prevent heart disease in those with type 2 diabetes.

It can be used as the only treatment for the condition, or in conjunction with other medications. This will be a decision that’s made by your doctor, taking into account the severity of your condition and your regular blood glucose levels.

Vokanamet isn’t a substitute for a healthy diet and exercise – it’s prescribed when these two lifestyle changes haven’t been enough to control your condition. Vokanamet should still be used in conjunction with these changes.

Can I take Vokanamet?

Although Vokanamet is a very effective treatment for type 2 diabetes, there are some other conditions that might prevent you from being able to take it. This is because it may cause adverse effects or worsen your other health issues. Some of the conditions that aren’t compatible with using Vokanamet include:

  • Being allergic to canagliflozin or metformin, or any other ingredients of Vokanamet
  • Liver problems
  • Severely reduced kidney function
  • Uncontrolled diabetes with hyperglycaemia, nausea, vomiting, diarrhoea, rapid weight loss, lactic acidosis or ketoacidosis
  • Severe infection
  • Dehydration
  • Diabetic pre-coma
  • Recent heart attack
  • Severe blood circulation difficulties
  • Drinking alcohol excessively
  • Heart failure
  • Type 1 diabetes
  • Stroke
  • Low blood pressure
  • Genital yeast infection
  • Lower limb amputation

You should visit your doctor if any of the above conditions or medical problems apply to you. You may still be able to take Vokanamet at a lower dose or with close monitoring. However, some of the conditions are listed due to the increased risk of experiencing something called lactic acidosis; a medical emergency.

What is lactic acidosis?

Whilst taking Vokanamet, there’s a chance that you might experience lactic acidosis, a condition which requires immediate medical attention. This risk is increased by having poor kidney function, uncontrolled diabetes, severe infection, prolonged fasting, drinking alcohol excessively, dehydration, liver problems and reduced supply of oxygen. This is why so many of the conditions are listed that patients must take extra care with, as if you have any of them as well as using Vokanamet, your risk of the condition is even further increased.

The symptoms of lactic acidosis are:

  • Vomiting
  • Abdominal pain
  • Muscle cramps
  • Feeling generally unwell
  • Extreme fatigue
  • Difficulty breathing
  • Reduced body temperature
  • Reduced heart rate

If you experience any of these symptoms, you should call 999 and state that you might be experiencing lactic acidosis.

Will Vokanamet interact with any other medicines?

Most drugs will interact with other medications, and Vokanamet is no exception to this. Some of the interactions might make one treatment less effective, or it might increase the risk or severity of side effects. However, not all interactions mean that you aren’t able to take Vokanamet; you might just need your dosages adjusting in order to take both medicines safely. The list of interactions include:

  • Insulin
  • Glimepiride
  • Glipizide
  • Sulphonylurea medications
  • Diuretics
  • St John’s Wort
  • Carbamazepine
  • Phenytoin
  • Phenobarbital
  • Medications for epilepsy
  • Efavirenz
  • Ritonavir
  • Medications for HIV
  • Rifampicin
  • Cholestyramine
  • Digoxin
  • Digitoxin
  • Dabigatron
  • Cimetidine
  • Corticosteroids
  • Salbutamol
  • Terbutaline
  • NSAIDs
  • COX-2 inhibitors
  • ACE inhibitors
  • Angiotensin II receptor antagonists

If you still aren’t sure whether your current medications are compatible with Vokanamet, you should take a list of your current drugs in to your local pharmacy and ask them to review the interactions. They should be able to tell you whether it’s safe for you to use Vokanamet or not.

If you do take any of the medicines on the list, or your pharmacist has told you that you’re taking another drug that might interact with Vokanamet, make an appointment with your doctor to discuss your options. For example, if you’re using insulin as well as Vokanamet, your dose may need to be adjusted so that you don’t suffer from hypoglycaemia.

What are the side effects of Vokanamet?

Vokanamet affects your body by lowering your blood glucose levels, but it can also cause some other symptoms that seem unrelated to the medicine’s goal. This is because of how it works in your body and the condition that it’s treating. Some of the most critical side effects that need urgent medical treatment include:

  • Severe allergic reaction
  • Lactic acidosis
  • Diabetic ketoacidosis
  • Dehydration
  • Hypoglycaemia

If you experience symptoms of any of the above, you should seek emergency treatment, calling 999 and stating your symptoms. Less critical side effects of the medication include:

  • Yeast infection of the genitals
  • Urinary tract infections (UTI)
  • Changes in urination habits
  • Constipation
  • Thirst
  • Nausea
  • Change in cholesterol and red blood cells
  • Rash/red skin
  • Hives
  • Changes in kidney function
  • Changes in potassium levels
  • Increased blood phosphate levels
  • Bone fracture
  • Kidney failure
  • Lower limb amputation
  • Difficulty pulling back foreskin

More side effects are listed in the patient information leaflet, and some of the ones listed here are rare and are unlikely to affect a majority of users. However, if you have any concerns about the side effects, this is something you should bring up with your doctor before starting treatment.

Please report any side effects you experience to your GP, even if they’re only mild.

How do you take Vokanamet?

Vokanamet should be taken as one tablet, twice a day. The dose of your tablet will depend on the severity of your condition and your blood glucose levels. This will be decided by your own GP. If you don’t know what dosage you need, please visit your doctor before ordering to make sure you’re on the right amount for your condition.

You should take Vokanamet with food, usually with breakfast and your evening meal. This reduces the risk of experiencing gastrointestinal issues.

Swallow the tablet whole with water, and if you take more than you should, ring 111 for advice, or dial 999 if you experience any of the critical symptoms mentioned earlier.

Dosage Instructions
Take ONE tablet TWICE a day
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Vokanamet Dosage Quantity Cost Including Consultation
Vokanamet 50mg/850mg 60 Tablets £53.99
Vokanamet 50mg/1000mg 60 Tablets £54.99
Vokanamet 50mg/850mg 120 Tablets £103.99
Vokanamet 50mg/1000mg 120 Tablets £104.99
Vokanamet 50mg/850mg 180 Tablets £148.99
Vokanamet 50mg/1000mg 180 Tablets £149.99

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Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

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All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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