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Xigduo

Xigduo is a treatment for diabetes which is typically used in combination with diet and exercise. It helps patients with diabetes in their efforts to keep their blood sugar levels at a healthy amount, something which takes work when they have this particular condition. Xigduo tablets contain two key ingredients which make certain changes in the body that aid the process of breaking down sugar.



Xigduo Patient Information Leaflet

Last Patient Information Leaflet Review: 22/01/2020



£ 59.99 InStock
Please note a final decision on a suitable medicine for your condition will be made by our prescriber once you have completed a consultation PLEASE CLICK HERE TO ANSWER SOME QUESTIONS ABOUT YOUR SYMPTOMS
Please note all the answers are reviewed by a doctor to assess eligibility
1
  • Allergy to dapagliflozin or metformin
  • History of diabetic coma
  • Uncontrolled diabetes with hypoerglycaemia, nausea, vomiting, diarrhoea, rapid weight loss, alctic acidosis or ketoacidosis
  • Severely reduced kidney function
  • Severe infection
  • Dehydration
  • Recent heart attack
  • Heart failure
  • Serious circulation problems
  • Breathing difficulties
  • Problems with your liver
  • You regularly drink a lot of alcohol
  • Type 1 diabetes
  • Recurrent infections of the urinary tract
2
  • Diuretics
  • Sulphonylurea medications
  • Insulin
  • Other treatments to lower blood glucose (unless your GP already prescribes this medication alongside them)
  • Cimetidine
  • Beta-2 agonists
  • Corticosteroids
  • NSAIDs and COX-2 inhibitors
  • ACE inhibitors
  • Angiotensin II receptor antagonists
3

Please use a minimum of 1 words.

4

Please use a minimum of 1 words.

5
  • You experience symptoms of lactic acidosis
  • You experience symptoms of ketoacidosis
  • You become dehydrated 
6
  • You have an allergy to dapagliflozin or metformin
  • You've used this treatment before and suffered from serious side effects
  • You're already using dapagliflozin or metformin for another condition
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Dr Daniel Cichi has 20 years experience as a doctor and now he is a senior GP. He worked in A&E departments, GP surgeries and on cruise ships.

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Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Xigduo?

Xigduo tablets are a medication used to treat type 2 diabetes. Used by adults aged 18 and above, this treatment is taken on a daily basis to keep the amount of sugar in the body at a healthy level. When exercise and diet is not enough to prevent symptoms of diabetes developing, a medication like Xigduo can be used for support.

How does Xigduo work?

When a patient is unable to make enough insulin naturally with their pancreas, or their body can’t use it properly, the amount of sugar that gets broken down while in the body is considerably less than normal. An abnormally high amount of sugar in the body is responsible for diabetes and the symptoms associated with the condition.

Xigduo is able to address this issue as it contains two medicines belonging to a group called oral anti-diabetics. They are called dapagliflozin and metformin. The former works to remove excess sugar from your body via your urine and the latter inhibits glucose production in the liver, reducing the total amount of sugar in your blood.

How do I use Xigduo?

This medication may possibly be prescribed together with other medicines that lower the amount of sugar in your blood. The exact amount of Xigduo you’ll take and at what strength the tablets will be will depend on certain details about your condition and the doses you currently take of metformin and/or individual tablets of dapagliflozin and metformin. Your doctor will provide guidance on what dosage suits you best.

The typical recommended dose is to take one tablet twice a day. The tablet should be swallowed whole with a glass of water and taken after food to reduce the risk of side effects in the stomach. It’s recommended that you take one of the tablets for the day in the morning (breakfast time) and the other in the evening (dinner time).

What are the side effects of Xigduo?

It is possible that you’ll experience side effects while taking Xigduo, but not all patients get them. If you do experience any that are particularly troubling or prolonged, then seek medical advice from your doctor or nearest hospital as soon as possible.

The most commonly reported side effects tied to this medication include the following:

  • Nausea and vomiting
  • Stomach aches
  • Loss of appetite
  • Diarrhoea
  • Genital infection (thrush) – Signs of this can include irritation, itching, unusual discharge or odour around your genitals
  • Back pain
  • Discomfort when urinating, passing more water than usual or need to urinate more often
  • Noticeable differences in how things taste
  • Dizziness
  • Rash
  • Changes in the amount of cholesterol or fats in your blood (shown in tests)
  • Increase in the amount of red blood cells in your blood (shown in tests)
  • Decreases in creatinine renal clearance (shown in tests)

You should stop taking this medication and seek medical help right away if you experience any of these serious side effects:

  • Lactic acidosis – Symptoms of this very rare but serious condition include vomiting, muscle cramps, severe tiredness and reduced body temperature and heartbeat
  • Dehydration – Signs of this issue include having a very dry or sticky mouth, feeling very thirsty and/or tired, a fast heartbeat and passing little to no water (urine)
  • Urinary tract infection – Symptoms of this infection include fever and/or chills, a burning sensation when urinating and pain in your back or side
  • Diabetic ketoacidosis – Symptoms can include rapid weight loss, excessive thirst, fast and deep breathing and unusual sleepiness or tiredness
  • Low blood sugar levels (hypoglycaemia) – Symptoms can include shaking, sweating, fast heartbeat and change in vision
  • Blood in your urine

Can I use Xigduo?

Certain circumstances regarding your health may mean you will have to avoid using Xigduo. That’s why it’s important to check you’re ok to use this medication before starting it. You should avoid taking Xigduo and seek alternative treatment if any of the following applies to you:

  • You have at some point in the past experienced a diabetic coma
  • You have uncontrolled diabetes along with a major health issue such as severe hyperglycaemia or ketoacidosis
  • You have severely reduced kidney function
  • You have some kind of severe infection
  • You are experiencing dehydration, due to an issue such as diarrhoea
  • You have recently had a heart attack
  • You suffer from heart failure or serious problems with your blood circulation or breathing
  • You have problems with your liver
  • You have type 1 diabetes
  • You are taking another medicine for diabetes which contains pioglitazone
  • You drink large amounts of alcohol, either every day or from time to time

It’s best to speak to a doctor or pharmacist for advice on the right steps to take if any of the above apply to you. You should also speak to a doctor or pharmacist as a precaution if any of these factors apply to you:

  • You are experiencing rapid weight loss, sickness, stomach pain, excessive thirst, fast and deep breathing or unusual sleepiness or tiredness
  • You have some sort of problem with how your kidney functions
  • You have a history of severe heart disease or have had a stroke in the past
  • You often get urinary tract infections
  • You are 75 years old or older

Another thing to speak to your doctor or pharmacist about (if relevant) is what other medications you are currently taking before you start Xigduo. It’s particularly important you mention any of the following medicines if you are currently using any:

  • Other medicines that lower the amount of sugar in your blood
  • Certain medicines for treating high blood pressure (particularly ACE inhibitors and angiotensin II receptor antagonists)
  • Medicines which increase urine production (diuretics)
  • Cimetidine (taken to treat stomach problems)
  • Bronchodilators (taken to treat asthma)
  • Corticosteroids (used for treating inflammation caused by diseases like asthma and arthritis)
  • Medicines that treat pain and inflammation (such as ibuprofen and celecoxib)

What if I take too much Xigduo?

If you take more of this medicine than you were meant to then it’s best to contact your doctor for advice. Taking too much Xigduo makes it more likely you could experience the serious side effect of lactic acidosis.

What if I forget to use Xigduo?

If you forget to take a dose of this medication, then take it as soon as you remember. If, however, you don’t remember it until it’s time for your next dose, then skip the missed dose and take the following doses at the usual time. Do not take a double dose to make up for a missed one.

Dosage Instructions
The recommended dose is one tablet twice a day.
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Xigduo Dosage Quantity Cost Including Consultation
Xigduo 5mg/850mg 56 tablets £59.99
Xigduo 5mg/850mg 112 tablets £117.99
Xigduo 5mg/850mg 168 tablets £175.99
Xigduo 5mg/1000mg 56 tablets £60.99
Xigduo 5mg/1000mg 112 tablets £118.99
Xigduo 5mg/1000mg 168 tablets £176.99

Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

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UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

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Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

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Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

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DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

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Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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