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Stop Smoking (Smoking Cessation)

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Zyban

Zyban tablets are a treatment prescribed to patients who are trying to stop smoking. The tablets are usually taken for 7 to 9 weeks and they contain a chemical compound which influences brain chemicals so that cravings for nicotine supplied by cigarettes will disappear. The exact amount of tablets patients will take during their course will depend on their age and other health factors.

Last PIL Review Date: 27/01/2020

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See Zyban Patient Information Leaflet

This medicine is not available to request via our online service. If you are still having trouble with your symptoms please visit the NHS website for services in your area.

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Dr Daniel Cichi has 20 years experience as a doctor and now he is a senior GP. He worked in A&E departments, GP surgeries and on cruise ships.

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Shamir is a well-respected pharmacist with extensive experience running online pharmacies in the UK.

What is Zyban?

Zyban is a prescription smoking cessation treatment. It is taken to stop smoking and is usually taken alongside motivational support, such as taking part in a ‘stop smoking’ programme. The size of the medication pack and the dosage instructions provided will depend on the age of the patient and the exact treatment required.

How does Zyban work?

Zyban contains a chemical compound called bupropion hydrochloride which stimulates the functions of various chemicals (neurotransmitters) in the brain. The treatment blocks the brain from absorbing mood regulating chemicals which can cause cravings for nicotine gained from smoking. By stopping the interference with brain chemicals, they become more active and less reliant on pleasure signals, and this reduces feelings of nicotine withdrawal in the patient.

How do I take Zyban and for how long?

There are different packs of Zyban available for those that are over and under the age of 65 and there are starting packs and continuation packs for each age group. The starting packs are used at the start of treatment and cover the first two weeks and the continuation packs are used after the initial two weeks are completed.

Typically, when people start taking Zyban, they will still be smoking cigarettes and patients are advised to keep on smoking during the first week of treatment. Patients will have a target stop smoking day ideally during the second week of treatment.

In the first week of treatment, the typical dosage is one tablet once a day during days 1 to 6. On the 7th day, the dosage increases to one tablet on two occasions per day. These tablets should be taken at least 8 hours apart, and not near to bedtime.

During the second week of treatment, patients will stop smoking and continue to take one tablet twice a day. You’ll continue to take one tablet twice a day in following weeks until you reach 9 weeks of treatment max. You may be advised to stop taking Zyban gradually during weeks 7-9. If you have not been able to stop smoking after 7 weeks, your doctor will advise you to stop taking this medication.

Your dosage may remain at one tablet once per day in all weeks depending on your circumstances. This is more likely to occur if any of the following apply to you:

  • You are aged over 65
  • You have a liver or kidney disease
  • You have a higher risk of fits

When taking Zyban tablets, they must be swallowed whole (you could take them with a glass of water). They can be taken with or without food. Don’t chew, crush or split these tablets because otherwise the medication will be released into your body too quickly and side effects, including fits, could occur. It’s also important to avoid taking them soon before bedtime as they can cause difficulty in sleeping.

What are the side effects of Zyban?

Various side effects could potentially emerge while taking Zyban, although not all users experience them. The most commonly reported side effect by patients is trouble sleeping, but the chances of this can be reduced if you avoid using this medication near to bedtime. Other side effects commonly reported by users include:

  • Difficulty concentrating
  • Feeling anxious or agitated
  • Feeling depressed
  • Feeling shaky
  • Headaches
  • Nausea and vomiting
  • Stomach pain or other upsets
  • Dry mouth or changes in taste of food

Other and more serious side effects, such as fits and allergic reactions are also possible but they are also rarely experienced by patients. If you do notice any side effects which are concerning, you should stop using this medication and contact your doctor immediately.

Can I use Zyban?

Before you start taking Zyban, you should check with your doctor that you don’t have any medical conditions that may prevent you from taking this treatment. You should also let your doctor or pharmacist know about any other medication you are currently using (or have recently used) as their effects or the effects of Zyban may be disrupted if there is a clash with certain treatments.

Avoid taking Zyban if any of the following apply to you:

  • You’re taking any other medicines that contain bupropion
  • You are pregnant, breast-feeding or think you may be pregnant
  • You have a condition that causes fits/seizures, such as epilepsy
  • You have or have previously had an eating disorder, such as bulimia
  • You have severe liver problems, such as cirrhosis
  • You have a brain tumour
  • You’re usually a heavy drink and you have recently stopped drinking alcohol
  • You have recently stopped taking sedatives or medicines to treat anxiety
  • You have a bipolar disorder
  • You’re taking medicines for depression or Parkinson’s disease which are called monoamine oxidase inhibitors (MAOIs), or have used them in the last 14 days.

There may be increased risk of experiencing fits if you take Zyban while also using any of the following medication:

  • Medicines for depression or other mental health problems
  • Theophylline (for asthma or lung disease)
  • Tramadol
  • Steroids (except creams and lotions for eye and skin conditions)
  • Quinolones
  • Stimulants or other medicines that control your weight or appetite
  • Medicines for treating malaria
  • Certain types of anti-histamines

Other particular medicines can also affect how Zyban works and increase the likelihood of experiencing side effects:

  • Some medicines that treat cancer (such as cyclophosphamide and ifosphamide
  • Some beta blockers (such as metoprolol)
  • Some medicines for irregular heart rhythm (such as propafanone and flecainide)
  • Ticlopidine or clopidogrel (both treat heart disease and strokes)
  • Treatments for HIV infection (such as ritonavir or efavirenz)

In addition, if you are taking tamoxifen (used to treat breast cancer), then the effects of this treatment could become less effective when used alongside Zyban.

What if I take too much Zyban?

If you take a larger dose of this medicine than you should, you should contact your doctor or nearest hospital emergency department right away. The chances of experiencing side effects will be greater than usual.

What if I forget to take Zyban?

If you forget a dose of this medication, then simply skit it and take the next tablet at the usual time. Do not take a double dose to make up for a forgotten one.

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Delivery Charges

The following delivery methods are currently available within the UK: All orders are sent in discreet, plain packaging.

UK Standard Delivery, £1.99

Order before 12pm to have your order delivered using Royal Mail Tracked 48 Service

standard UK delivery within 3-5 working days

Additional terms and conditions apply.

UK Express Delivery, £2.99

Order before 12pm to have your order delivered using the Express delivery service* (deliveries are made Monday - Saturday)

If you order after 12pm, your order will be dispatched the next working day and will be with you within 48 hours once dispatched. This excludes weekends and bank holidays

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Anytime, £4.99 (This service includes Saturday)

Order before 12pm to have your order delivered using Royal Mail Special Delivery Service, which includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 1pm, £7.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 1pm next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

Royal Mail Special Delivery Next Day Before 9am, £14.99 (This service includes Saturday)

Order before 12pm to have your order delivered before 9am next day using Royal Mail Special Delivery service, this also includes Saturday deliveries.

Additional terms and conditions apply.

DPD Next Day Delivery, £4.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 12 Noon, £9.99 (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 12 noon the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Next Day Delivery, by 10:30am, £14.99  (Monday - Friday only. This service does not include Saturday)

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am the following working day

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, £14.99

Orders signed by the doctor before 12 noon the day before will be delivered the following Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply

DPD Saturday Delivery, by 12:00am, £21.99

Orders signed by the doctor before 12 noon the day before will be delivered by 12:00am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply.

DPD Saturday Delivery, by 10:30am, £29.99

Orders signed by the doctor before 12 noon the day before will be delivered by 10:30am Saturday

If your order is signed by the doctor after 12 noon, your order will be delivered within 2 working days

Additional terms and conditions apply, please see below.

US and outside the UK

Unfortunately, we can't process orders from outside the UK at this time.


Terms and Conditions

Delivery options exclude Bank Holidays, public holidays and Sundays.All deliveries are subject to Doctor-4-u successfully receiving payment and prescription being approved by the doctor.

All purchases require additional approval, which will involve completion of an online questionnaire and any subsequent approval.

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